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https://ah.lib.nccu.edu.tw/handle/140.119/65229| 題名: | An expedient synthesis of honokiol and its analogues as potential neuropreventive agents | 作者: | Tripathi, Subhankar ; Chan, Ming-Huan ; Chen, Chinpiao 詹銘煥 |
貢獻者: | 神科所 | 關鍵詞: | Honokiol; Neuropreventive; Parkinson’s disease; Suzuki–Miyaura cross coupling; Claisen rearrangement | 日期: | 2012 | 上傳時間: | 9-Apr-2014 | 摘要: | An efficient synthesis of honokiol with Suzuki–Miyaura cross coupling obtained an overall yield of 45%. The proposed approach successfully synthesized several structurally similar alkyl, alkenyl and alkynyl analogues, seven of which showed potential neuropreventive activity against MPP+-induced and CHP/TBHP oxidative stress induced neuroblastoma cell death. | 關聯: | Bioorg Med Chem Lett,22(1), 216-221 | 資料來源: | http://dx.doi.org/10.1016/j.bmcl.2011.11.030 | 資料類型: | article |
| Appears in Collections: | 期刊論文 |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| 216-221.pdf | 567.3 kB | Adobe PDF2 | View/Open |
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