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https://ah.lib.nccu.edu.tw/handle/140.119/63028
題名: | Use of a Modified Spatial-Context Memory Test to Detect Amnestic Mild Cognitive Impairment. | 作者: | 楊建銘 Yang, Chien-Ming ; Wang, Hsuan-Min ; Kuo, Wan-Chin ; Huang, Chin-Chang ; Kuo, Hung-Chou |
貢獻者: | 心理系 | 關鍵詞: | Alzheimer disease ; Amnesia ; Biology ; Cognitive neurology ; Cognitive neuroscience ; Cognitive psychology ; Dementia ; Diagnostic medicine ; Medicine ; Memory ; Mental health ; Neurological Disorders ; Neurology ; Neuroscience ; Psychiatry ; Psychology ; Research Article ; Test evaluation | 日期: | 2013 | 上傳時間: | 26-Dec-2013 | 摘要: | In this study we sought to differentiate participants with amnestic mild cognitive impairment (a-MCI) from those with mild dementia of Alzheimer’s type (m-DAT) and normal controls by modifying an existing test of spatial context memory (SCMT) designed so as to evaluate the function of brain regions affected in early m-DAT. We found that participants with a-MCI had better total scores on our modified SCMT than those with m-DAT. Furthermore, the locational memory subtest was able to discriminate between those with a-MCI and m-DAT. Additionally, compared with other screening tests, our spatial context memory test showed high sensitivity and specificity in discerning those with a-MCI from the normal population but, was relatively ineffective in discriminating a-MCI patients from those with m-DAT. We conclude that our modified test of SCMT is an effective tool for discriminating a-MCI from m-DAT and does so by detecting differences in locational memory. | 關聯: | PLoS ONE, 8(2), 1-8 | 資料類型: | article | DOI: | http://dx.doi.org/10.1371/journal.pone.0057030 |
Appears in Collections: | 期刊論文 |
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