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題名: | Resting state glutamate predicts elevated pre-stimulus alpha during self-relatedness – A combined EEG-MRS study on rest-self overlap. | 作者: | 顏乃欣 Yen, Nai-Shing;Tsai, Shang-Yueh;Northoff, Georg |
貢獻者: | 心理系 | 日期: | 2015 | 上傳時間: | 10-Nov-2015 | 摘要: | Recent studies have demonstrated neural overlap between resting state activity and self-referential processing. This \"rest-self\" overlap occurs especially in anterior cortical midline structures like the perigenual anterior cingulate cortex (PACC). However, the exact neurotemporal and biochemical mechanisms remain to be identified. Therefore, we conducted a combined electroencephalography (EEG)-magnetic resonance spectroscopy (MRS) study. EEG focused on pre-stimulus (e.g., prior to stimulus presentation or perception) power changes to assess the degree to which those changes can predict subjects` perception (and judgment) of subsequent stimuli as high or low self-related. MRS measured resting state concentration of glutamate, focusing on PACC. High pre-stimulus (e.g., prior to stimulus presentation or perception) alpha power significantly correlated with both perception of stimuli judged to be highly self-related and with resting state glutamate concentrations in the PACC. In sum, our results show (i) pre-stimulus (e.g., prior to stimulus presentation or perception) alpha power and resting state glutamate concentration to mediate rest-self overlap that (ii) dispose or incline subjects to assign high degrees of self-relatedness to perceptual stimuli. | 關聯: | Social Neuroscience | 資料類型: | article | DOI: | http://dx.doi.org/10.1080/17470919.2015.1072582 |
Appears in Collections: | 期刊論文 |
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