Please use this identifier to cite or link to this item:
https://ah.lib.nccu.edu.tw/handle/140.119/97014
題名: | TCS: a web server for multiple sequence alignment evaluation and phylogenetic reconstruction | 作者: | 張家銘 Chang, Jia-Ming;Tommaso, Paolo Di;Lefort, Vincent;Gascuel, Olivier;Notredame, Cedric |
貢獻者: | 資科系 | 日期: | Jul-2015 | 上傳時間: | 30-May-2016 | 摘要: | This article introduces the Transitive Consistency Score (TCS) web server; a service making it possible to estimate the local reliability of protein multiple sequence alignments (MSAs) using the TCS index. The evaluation can be used to identify the aligned positions most likely to contain structurally analogous residues and also most likely to support an accurate phylogenetic reconstruction. The TCS scoring scheme has been shown to be accurate predictor of structural alignment correctness among commonly used methods. It has also been shown to outperform common filtering schemes like Gblocks or trimAl when doing MSA post-processing prior to phylogenetic tree reconstruction. The web server is available from http://tcoffee.crg.cat/tcs | 關聯: | Nucleic Acids Research, Vol.43, No.W1, pp.W3-6 | 資料類型: | article | DOI: | http://dx.doi.org/10.1093/nar/gkv310 |
Appears in Collections: | 期刊論文 |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
W3.full.pdf | 1.22 MB | Adobe PDF2 | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.