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題名 Analysis of noisy survival data with graphical proportional hazards measurement error models
作者 陳立榜
Chen, Li-Pang
Yi, Grace Y.
貢獻者 統計系
關鍵詞 error-prone variable; graphical model; high-dimensionality; simulation-extrapolation; survivalanalysis
日期 2021-09
上傳時間 21-Sep-2022 11:45:24 (UTC+8)
摘要 In survival data analysis, the Cox proportional hazards (PH) model is perhaps the most widely used model to feature the dependence of survival times on covariates. While many inference methods have been developed under such a model or its variants, those models are not adequate for handling data with complex structured covariates. High-dimensional survival data often entail several features: (1) many covariates are inactive in explaining the survival information, (2) active covariates are associated in a network structure, and (3) some covariates are error-contaminated. To hand such kinds of survival data, we propose graphical PH measurement error models and develop inferential procedures for the parameters of interest. Our proposed models significantly enlarge the scope of the usual Cox PH model and have great flexibility in characterizing survival data. Theoretical results are established to justify the proposed methods. Numerical studies are conducted to assess the performance of the proposed methods.
關聯 Biometrics, Vol.77, No.3, pp.956-969
資料類型 article
DOI https://doi.org/10.1111/biom.13331
dc.contributor 統計系
dc.creator (作者) 陳立榜
dc.creator (作者) Chen, Li-Pang
dc.creator (作者) Yi, Grace Y.
dc.date (日期) 2021-09
dc.date.accessioned 21-Sep-2022 11:45:24 (UTC+8)-
dc.date.available 21-Sep-2022 11:45:24 (UTC+8)-
dc.date.issued (上傳時間) 21-Sep-2022 11:45:24 (UTC+8)-
dc.identifier.uri (URI) http://nccur.lib.nccu.edu.tw/handle/140.119/142017-
dc.description.abstract (摘要) In survival data analysis, the Cox proportional hazards (PH) model is perhaps the most widely used model to feature the dependence of survival times on covariates. While many inference methods have been developed under such a model or its variants, those models are not adequate for handling data with complex structured covariates. High-dimensional survival data often entail several features: (1) many covariates are inactive in explaining the survival information, (2) active covariates are associated in a network structure, and (3) some covariates are error-contaminated. To hand such kinds of survival data, we propose graphical PH measurement error models and develop inferential procedures for the parameters of interest. Our proposed models significantly enlarge the scope of the usual Cox PH model and have great flexibility in characterizing survival data. Theoretical results are established to justify the proposed methods. Numerical studies are conducted to assess the performance of the proposed methods.
dc.format.extent 98 bytes-
dc.format.mimetype text/html-
dc.relation (關聯) Biometrics, Vol.77, No.3, pp.956-969
dc.subject (關鍵詞) error-prone variable; graphical model; high-dimensionality; simulation-extrapolation; survivalanalysis
dc.title (題名) Analysis of noisy survival data with graphical proportional hazards measurement error models
dc.type (資料類型) article
dc.identifier.doi (DOI) 10.1111/biom.13331
dc.doi.uri (DOI) https://doi.org/10.1111/biom.13331