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題名 Semiparametric methods for left-truncated and right-censored survival data with covariate measurement error
作者 陳立榜
Chen, Li-Pang
Yi, Grace Y.
貢獻者 統計系
關鍵詞 Cox model; Efficiency; Left-truncation; Measurement error; Right censoring
日期 2021-06
上傳時間 21-九月-2022 11:45:49 (UTC+8)
摘要 Many methods have been developed for analyzing survival data which are commonly right-censored. These methods, however, are challenged by complex features pertinent to the data collection as well as the nature of data themselves. Typically, biased samples caused by left-truncation (or length-biased sampling) and measurement error often accompany survival analysis. While such data frequently arise in practice, little work has been available to simultaneously address these features. In this paper, we explore valid inference methods for handling left-truncated and right-censored survival data with measurement error under the widely used Cox model. We first exploit a flexible estimator for the survival model parameters which does not require specification of the baseline hazard function. To improve the efficiency, we further develop an augmented nonparametric maximum likelihood estimator. We establish asymptotic results and examine the efficiency and robustness issues for the proposed estimators. The proposed methods enjoy appealing features that the distributions of the covariates and of the truncation times are left unspecified. Numerical studies are reported to assess the finite sample performance of the proposed methods.
關聯 Annals of the Institute of Statistical Mathematics, Vol.73, pp.481-517
資料類型 article
DOI https://doi.org/10.1007/s10463-020-00755-2
dc.contributor 統計系
dc.creator (作者) 陳立榜
dc.creator (作者) Chen, Li-Pang
dc.creator (作者) Yi, Grace Y.
dc.date (日期) 2021-06
dc.date.accessioned 21-九月-2022 11:45:49 (UTC+8)-
dc.date.available 21-九月-2022 11:45:49 (UTC+8)-
dc.date.issued (上傳時間) 21-九月-2022 11:45:49 (UTC+8)-
dc.identifier.uri (URI) http://nccur.lib.nccu.edu.tw/handle/140.119/142022-
dc.description.abstract (摘要) Many methods have been developed for analyzing survival data which are commonly right-censored. These methods, however, are challenged by complex features pertinent to the data collection as well as the nature of data themselves. Typically, biased samples caused by left-truncation (or length-biased sampling) and measurement error often accompany survival analysis. While such data frequently arise in practice, little work has been available to simultaneously address these features. In this paper, we explore valid inference methods for handling left-truncated and right-censored survival data with measurement error under the widely used Cox model. We first exploit a flexible estimator for the survival model parameters which does not require specification of the baseline hazard function. To improve the efficiency, we further develop an augmented nonparametric maximum likelihood estimator. We establish asymptotic results and examine the efficiency and robustness issues for the proposed estimators. The proposed methods enjoy appealing features that the distributions of the covariates and of the truncation times are left unspecified. Numerical studies are reported to assess the finite sample performance of the proposed methods.
dc.format.extent 106 bytes-
dc.format.mimetype text/html-
dc.relation (關聯) Annals of the Institute of Statistical Mathematics, Vol.73, pp.481-517
dc.subject (關鍵詞) Cox model; Efficiency; Left-truncation; Measurement error; Right censoring
dc.title (題名) Semiparametric methods for left-truncated and right-censored survival data with covariate measurement error
dc.type (資料類型) article
dc.identifier.doi (DOI) 10.1007/s10463-020-00755-2
dc.doi.uri (DOI) https://doi.org/10.1007/s10463-020-00755-2