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題名 Risk of rapid progression to dialysis in patients with type 2 diabetes mellitus with and without diabetes-related complications at diagnosis
作者 吳珮瑀
Wu, Pei-Yu;Shih, Hong-Mo;Tsai, Wen-Chen;Chiu, Li-Ting;Kung, Pei-Tseng
貢獻者 教育學院
日期 2023-09
上傳時間 20-二月-2024 14:00:30 (UTC+8)
摘要 Many adults with diabetes mellitus are unaware worldwide. The study objectives aimed to evaluate the risk of dialysis within 5 years of diagnosis between patients with newly diagnosed diabetes with and without diabetes-related complications. A retrospective longitudinal nationwide cohort study was conducted. Patients diagnosed with diabetes between 2005 and 2013 were followed up until 2018. They were categorized based on the presence or absence of complications, the number of complications, and the diabetes complications severity index (DCSI) scores. Dialysis outcomes were determined through the Registry of Catastrophic Illness from the National Health Insurance Research Database. Among the analyzed patients, 25.38% had complications at diagnosis. Patients with complications at diagnosis had a significantly higher risk of dialysis within 5 years (adjusted hazard ratio: 9.55, 95% confidence interval CI 9.02–10.11). Increasing DCSI scores and the number of complications were associated with higher dialysis risks. Patients with one complication had a 7.26-times higher risk (95% CI 6.83–7.71), while those with ≥ 3 complications had a 36.12-times higher risk (95% CI 32.28–40.41). In conclusion, newly diagnosed diabetes patients with complications face an increased risk of dialysis within 5 years. The severity and number of complications are directly linked to the risk of dialysis within this timeframe.
關聯 Scientific Reports, Vol.13, 16366
資料類型 article
DOI https://doi.org/10.1038/s41598-023-43513-z
dc.contributor 教育學院
dc.creator (作者) 吳珮瑀
dc.creator (作者) Wu, Pei-Yu;Shih, Hong-Mo;Tsai, Wen-Chen;Chiu, Li-Ting;Kung, Pei-Tseng
dc.date (日期) 2023-09
dc.date.accessioned 20-二月-2024 14:00:30 (UTC+8)-
dc.date.available 20-二月-2024 14:00:30 (UTC+8)-
dc.date.issued (上傳時間) 20-二月-2024 14:00:30 (UTC+8)-
dc.identifier.uri (URI) https://nccur.lib.nccu.edu.tw/handle/140.119/149896-
dc.description.abstract (摘要) Many adults with diabetes mellitus are unaware worldwide. The study objectives aimed to evaluate the risk of dialysis within 5 years of diagnosis between patients with newly diagnosed diabetes with and without diabetes-related complications. A retrospective longitudinal nationwide cohort study was conducted. Patients diagnosed with diabetes between 2005 and 2013 were followed up until 2018. They were categorized based on the presence or absence of complications, the number of complications, and the diabetes complications severity index (DCSI) scores. Dialysis outcomes were determined through the Registry of Catastrophic Illness from the National Health Insurance Research Database. Among the analyzed patients, 25.38% had complications at diagnosis. Patients with complications at diagnosis had a significantly higher risk of dialysis within 5 years (adjusted hazard ratio: 9.55, 95% confidence interval CI 9.02–10.11). Increasing DCSI scores and the number of complications were associated with higher dialysis risks. Patients with one complication had a 7.26-times higher risk (95% CI 6.83–7.71), while those with ≥ 3 complications had a 36.12-times higher risk (95% CI 32.28–40.41). In conclusion, newly diagnosed diabetes patients with complications face an increased risk of dialysis within 5 years. The severity and number of complications are directly linked to the risk of dialysis within this timeframe.
dc.format.extent 106 bytes-
dc.format.mimetype text/html-
dc.relation (關聯) Scientific Reports, Vol.13, 16366
dc.title (題名) Risk of rapid progression to dialysis in patients with type 2 diabetes mellitus with and without diabetes-related complications at diagnosis
dc.type (資料類型) article
dc.identifier.doi (DOI) 10.1038/s41598-023-43513-z
dc.doi.uri (DOI) https://doi.org/10.1038/s41598-023-43513-z