| dc.contributor | 政大統計系 | en_US |
| dc.creator (作者) | 高立箴;陳麗霞 | zh_TW |
| dc.creator (作者) | Kao, Lie-Jane;Chen, Li-Shya | en_US |
| dc.date (日期) | 2012-04 | en_US |
| dc.date.accessioned | 12-十二月-2013 18:02:59 (UTC+8) | - |
| dc.date.available | 12-十二月-2013 18:02:59 (UTC+8) | - |
| dc.date.issued (上傳時間) | 12-十二月-2013 18:02:59 (UTC+8) | - |
| dc.identifier.uri (URI) | http://nccur.lib.nccu.edu.tw/handle/140.119/62434 | - |
| dc.description.abstract (摘要) | In this article, the time from the start of chemotherapy randomization until cancer relapse is of primary interest. Here, cancer relapse refers to the appearance of the first observable malignant clone after therapy. A dynamic model for cancer relapse after chemotherapy is developed. The model differs from the traditional cure rate models in that it takes into consideration the growth kinetics of malignant tumors using a two-stage carcinogenesis model. The survival and hazard functions for cancer relapse time are derived, and a simulation study is performed to validate the underlying model. | en_US |
| dc.language.iso | en_US | - |
| dc.relation (關聯) | Communications in Statistics--Theorey and Methods, 41(10), 1701-1720 | en_US |
| dc.subject (關鍵詞) | Cancer relapse;Chemotherapy randomization;Cure rate;Observable malignant clone;Poisson cluster process;Two-stage carcinogenesis model | en_US |
| dc.title (題名) | The Dynamic Model for Cancer Relapse Based on Two-stage Model of Carcinogenesis | en_US |
| dc.type (資料類型) | article | en |
| dc.identifier.doi (DOI) | 10.1080/03610926.2012.719121 | - |
| dc.doi.uri (DOI) | http://dx.doi.org/10.1080/03610926.2012.719121 | - |
