Please use this identifier to cite or link to this item:
https://ah.lib.nccu.edu.tw/handle/140.119/116900
DC Field | Value | Language |
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dc.contributor | 應物所 | zh_Tw |
dc.creator | 蔡尚岳 | zh_TW |
dc.creator | Hsu, Yi-Cheng | en_US |
dc.creator | Chu, Ying-Hua | en_US |
dc.creator | Tsai, Shang-Yueh | en_US |
dc.creator | Kuo, Wen-Jui | en_US |
dc.creator | Chang, Chun-Yuan | en_US |
dc.date | 2017-12 | |
dc.date.accessioned | 2018-04-18T06:45:31Z | - |
dc.date.available | 2018-04-18T06:45:31Z | - |
dc.date.issued | 2018-04-18T06:45:31Z | - |
dc.identifier.uri | http://nccur.lib.nccu.edu.tw/handle/140.119/116900 | - |
dc.description.abstract | (BOLD) signals with high sensitivity and specificity. Here we propose a novel method: simultaneous multi-slice inverse imaging (SMS-InI) — a combination of simultaneous multi-slice excitation, simultaneous echo refocusing (SER), blipped controlled aliasing in parallel imaging echo-planar imaging (EPI), and regularized image reconstruction. Using a 32-channel head coil array on a 3 T scanner, SMS-InI achieves nominal isotropic 5-mm spatial resolution and 10 Hz sampling rate at the whole-brain level. Compared with traditional inverse imaging, we found that SMS-InI has higher spatial resolution with lower signal leakage and higher time-domain signal-to-noise ratio with the optimized regularization parameter in the reconstruction. SMS-InI achieved higher effective resolution and higher detection power in detecting visual cortex activity than InI. SMS-InI also detected subcortical fMRI signals with the similar sensitivity and localization accuracy like EPI. The spatiotemporal resolution of SMS-InI was used to reveal that presenting visual stimuli with 0.2 s latency between left and right visual hemifield led to 0.2 s relative hemodynamic response latency between the left and right visual cortices. Together, these results indicate that SMS-InI is a useful tool in measuring cortical and subcortical hemodynamic responses with high spatiotemporal resolution. | en_US |
dc.format.extent | 3411915 bytes | - |
dc.format.mimetype | application/pdf | - |
dc.relation | Scientific Reports, 2017; 7: 17019. | |
dc.title | Simultaneous multi-slice inverse imaging of the human brain | en_US |
dc.type | article | |
dc.identifier.doi | 10.1038/s41598-017-16976-0 | |
dc.doi.uri | https://dx.doi.org/10.1038%2Fs41598-017-16976-0 | |
item.openairetype | article | - |
item.grantfulltext | restricted | - |
item.fulltext | With Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
Appears in Collections: | 期刊論文 |
Files in This Item:
File | Description | Size | Format | |
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41598_2017_Article_16976.pdf | 3.33 MB | Adobe PDF2 | View/Open |
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