Please use this identifier to cite or link to this item:
https://ah.lib.nccu.edu.tw/handle/140.119/112534
DC Field | Value | Language |
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dc.contributor | 心理系 | zh_TW |
dc.creator | 楊啟正 | zh_TW |
dc.creator | Pan, M.-K. | en_US |
dc.creator | Huang, S.-C. | en_US |
dc.creator | Lo, Y.-C. | en_US |
dc.creator | Yang, Chih-Chao | en_US |
dc.creator | Cheng, T.-W. | en_US |
dc.creator | Yang, Chi-Cheng | en_US |
dc.creator | Hua, M.-S. | en_US |
dc.creator | Tseng, M.-J. Lee and W.-Y.I. | en_US |
dc.date | 2013-05 | |
dc.date.accessioned | 2017-09-06T08:30:01Z | - |
dc.date.available | 2017-09-06T08:30:01Z | - |
dc.date.issued | 2017-09-06T08:30:01Z | - |
dc.identifier.uri | http://nccur.lib.nccu.edu.tw/handle/140.119/112534 | - |
dc.description.abstract | BACKGROUND AND PURPOSE: ARHSP-TCC is characterized by progressive leg spasticity, ataxia, and cognitive dysfunction. Although mutations in the human SPG11 gene were identified as responsible for ARHSP-TCC, the cerebral fiber integrity has not been assessed systemically. The objective of this study was to assess cerebral fiber integrity and its clinical significance in patients with ARHSP-TCC. MATERIALS AND METHODS: Five patients from 2 families who were clinically and genetically confirmed to have ARHSP-TCC were examined by neuropsychological evaluation and DSI of the brain. We performed voxel-based GFA analysis for global white matter evaluation, tractography-based analysis for tract-to-tract comparisons, and tract-specific analysis of the CST to evaluate microstructural integrity along the axonal direction. | en_US |
dc.format.extent | 2158937 bytes | - |
dc.format.mimetype | application/pdf | - |
dc.relation | American Journal of Nuclear Radiology, Vol.34, No.5, pp.990-996 | en_US |
dc.title | Microstructural integrity of cerebral fiber tracts in hereditary spastic paraparesis with SPG11 mutation. | en_US |
dc.type | article | |
dc.identifier.doi | 10.3174/ajnr.A3330 | |
dc.doi.uri | https://doi.org/10.3174/ajnr.A3330 | |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.grantfulltext | restricted | - |
item.fulltext | With Fulltext | - |
item.openairetype | article | - |
item.cerifentitytype | Publications | - |
Appears in Collections: | 期刊論文 |
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