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題名 Multiple sequence alignment modeling: methods and applications
作者 張家銘
Chatzou, Maria;Magis, Cedrik;Chang, Jia-Ming;Kemena, Carsten;Bussotti, Giovanni;Erb, Ionas
貢獻者 資科系
關鍵詞 multiple sequence alignments ; protein alignments ; alignment benchmarks ; alignment reliability measures ; RNA alignments ; DNA alignments
日期 2015-11
上傳時間 30-May-2016 17:23:45 (UTC+8)
摘要 This review provides an overview on the development of Multiple sequence alignment (MSA) methods and their main applications. It is focused on progress made over the past decade. The three first sections review recent algorithmic developments for protein, RNA/DNA and genomic alignments. The fourth section deals with benchmarks and explores the relationship between empirical and simulated data, along with the impact on method developments. The last part of the review gives an overview on available MSA local reliability estimators and their dependence on various algorithmic properties of available methods.
關聯 Briefings in Bioinformatics
資料類型 article
DOI http://dx.doi.org/10.1093/bib/bbv099
dc.contributor 資科系
dc.creator (作者) 張家銘zh_TW
dc.creator (作者) Chatzou, Maria;Magis, Cedrik;Chang, Jia-Ming;Kemena, Carsten;Bussotti, Giovanni;Erb, Ionas
dc.date (日期) 2015-11
dc.date.accessioned 30-May-2016 17:23:45 (UTC+8)-
dc.date.available 30-May-2016 17:23:45 (UTC+8)-
dc.date.issued (上傳時間) 30-May-2016 17:23:45 (UTC+8)-
dc.identifier.uri (URI) http://nccur.lib.nccu.edu.tw/handle/140.119/97010-
dc.description.abstract (摘要) This review provides an overview on the development of Multiple sequence alignment (MSA) methods and their main applications. It is focused on progress made over the past decade. The three first sections review recent algorithmic developments for protein, RNA/DNA and genomic alignments. The fourth section deals with benchmarks and explores the relationship between empirical and simulated data, along with the impact on method developments. The last part of the review gives an overview on available MSA local reliability estimators and their dependence on various algorithmic properties of available methods.
dc.format.extent 100 bytes-
dc.format.mimetype text/html-
dc.relation (關聯) Briefings in Bioinformatics
dc.subject (關鍵詞) multiple sequence alignments ; protein alignments ; alignment benchmarks ; alignment reliability measures ; RNA alignments ; DNA alignments
dc.title (題名) Multiple sequence alignment modeling: methods and applications
dc.type (資料類型) article
dc.identifier.doi (DOI) 10.1093/bib/bbv099
dc.doi.uri (DOI) http://dx.doi.org/10.1093/bib/bbv099