| dc.contributor | 資科系 | |
| dc.creator (作者) | 張家銘 | zh_TW |
| dc.creator (作者) | Chang, Jia-Ming;Tommaso, Paolo Di;Lefort, Vincent;Gascuel, Olivier;Notredame, Cedric | |
| dc.date (日期) | 2015-07 | |
| dc.date.accessioned | 30-May-2016 17:24:39 (UTC+8) | - |
| dc.date.available | 30-May-2016 17:24:39 (UTC+8) | - |
| dc.date.issued (上傳時間) | 30-May-2016 17:24:39 (UTC+8) | - |
| dc.identifier.uri (URI) | http://nccur.lib.nccu.edu.tw/handle/140.119/97014 | - |
| dc.description.abstract (摘要) | This article introduces the Transitive Consistency Score (TCS) web server; a service making it possible to estimate the local reliability of protein multiple sequence alignments (MSAs) using the TCS index. The evaluation can be used to identify the aligned positions most likely to contain structurally analogous residues and also most likely to support an accurate phylogenetic reconstruction. The TCS scoring scheme has been shown to be accurate predictor of structural alignment correctness among commonly used methods. It has also been shown to outperform common filtering schemes like Gblocks or trimAl when doing MSA post-processing prior to phylogenetic tree reconstruction. The web server is available from http://tcoffee.crg.cat/tcs | |
| dc.format.extent | 1244582 bytes | - |
| dc.format.mimetype | application/pdf | - |
| dc.relation (關聯) | Nucleic Acids Research, Vol.43, No.W1, pp.W3-6 | |
| dc.title (題名) | TCS: a web server for multiple sequence alignment evaluation and phylogenetic reconstruction | |
| dc.type (資料類型) | article | |
| dc.identifier.doi (DOI) | 10.1093/nar/gkv310 | |
| dc.doi.uri (DOI) | http://dx.doi.org/10.1093/nar/gkv310 | |
