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題名 Evident cognitive impairments in seemingly recovered patients after midazolam-based light sedation during diagnostic endoscopy.
作者 楊啟正
Hsu, Yen-Hsuan
Lin, Feng-Sheng
Yang, Chi-Cheng
Lin, Chih-Peng
Hua, Mau-Sun
Sun, Wei-Zen
貢獻者 心理系
日期 2015-06
上傳時間 6-Sep-2017 16:29:22 (UTC+8)
摘要 BACKGROUND/PURPOSE: Midazolam is a widely used sedative agent during colonoscopy, with cognitive toxicity. However, the potential cognitive hazard of midazolam-based light sedation has not been sufficiently examined. We aimed to examine the cognitive safety and vulnerability profile under midazolam light sedation, with a particular focus on individual variations. METHODS: We conducted a prospective case-controlled study in an academic hospital. In total, 30 patients undergoing sedative colonoscopy as part of a health check-up were recruited. Neuropsychological testing on the full cognitive spectrum was evaluated at 15 minutes and 120 minutes after low-dose midazolam administration. The modified reliable change index (RCI) was used for intrapersonal comparisons and controlling for practice effects.
關聯 Journal of the Formosan Medical Association, Vol.114, No.6, pp.489-497
資料類型 article
DOI https://doi.org/10.1016/j.jfma.2013.07.018
dc.contributor 心理系zh_TW
dc.creator (作者) 楊啟正zh_TW
dc.creator (作者) Hsu, Yen-Hsuanen_US
dc.creator (作者) Lin, Feng-Shengen_US
dc.creator (作者) Yang, Chi-Chengen_US
dc.creator (作者) Lin, Chih-Pengen_US
dc.creator (作者) Hua, Mau-Sunen_US
dc.creator (作者) Sun, Wei-Zenen_US
dc.date (日期) 2015-06
dc.date.accessioned 6-Sep-2017 16:29:22 (UTC+8)-
dc.date.available 6-Sep-2017 16:29:22 (UTC+8)-
dc.date.issued (上傳時間) 6-Sep-2017 16:29:22 (UTC+8)-
dc.identifier.uri (URI) http://nccur.lib.nccu.edu.tw/handle/140.119/112530-
dc.description.abstract (摘要) BACKGROUND/PURPOSE: Midazolam is a widely used sedative agent during colonoscopy, with cognitive toxicity. However, the potential cognitive hazard of midazolam-based light sedation has not been sufficiently examined. We aimed to examine the cognitive safety and vulnerability profile under midazolam light sedation, with a particular focus on individual variations. METHODS: We conducted a prospective case-controlled study in an academic hospital. In total, 30 patients undergoing sedative colonoscopy as part of a health check-up were recruited. Neuropsychological testing on the full cognitive spectrum was evaluated at 15 minutes and 120 minutes after low-dose midazolam administration. The modified reliable change index (RCI) was used for intrapersonal comparisons and controlling for practice effects.en_US
dc.format.extent 830269 bytes-
dc.format.mimetype application/pdf-
dc.relation (關聯) Journal of the Formosan Medical Association, Vol.114, No.6, pp.489-497en_US
dc.title (題名) Evident cognitive impairments in seemingly recovered patients after midazolam-based light sedation during diagnostic endoscopy.en_US
dc.type (資料類型) article
dc.identifier.doi (DOI) 10.1016/j.jfma.2013.07.018
dc.doi.uri (DOI) https://doi.org/10.1016/j.jfma.2013.07.018