| dc.contributor | 心理系 | zh_TW |
| dc.creator (作者) | 楊啟正 | zh_TW |
| dc.creator (作者) | Pan, M.-K. | en_US |
| dc.creator (作者) | Huang, S.-C. | en_US |
| dc.creator (作者) | Lo, Y.-C. | en_US |
| dc.creator (作者) | Yang, Chih-Chao | en_US |
| dc.creator (作者) | Cheng, T.-W. | en_US |
| dc.creator (作者) | Yang, Chi-Cheng | en_US |
| dc.creator (作者) | Hua, M.-S. | en_US |
| dc.creator (作者) | Tseng, M.-J. Lee and W.-Y.I. | en_US |
| dc.date (日期) | 2013-05 | |
| dc.date.accessioned | 6-Sep-2017 16:30:01 (UTC+8) | - |
| dc.date.available | 6-Sep-2017 16:30:01 (UTC+8) | - |
| dc.date.issued (上傳時間) | 6-Sep-2017 16:30:01 (UTC+8) | - |
| dc.identifier.uri (URI) | http://nccur.lib.nccu.edu.tw/handle/140.119/112534 | - |
| dc.description.abstract (摘要) | BACKGROUND AND PURPOSE: ARHSP-TCC is characterized by progressive leg spasticity, ataxia, and cognitive dysfunction. Although mutations in the human SPG11 gene were identified as responsible for ARHSP-TCC, the cerebral fiber integrity has not been assessed systemically. The objective of this study was to assess cerebral fiber integrity and its clinical significance in patients with ARHSP-TCC. MATERIALS AND METHODS: Five patients from 2 families who were clinically and genetically confirmed to have ARHSP-TCC were examined by neuropsychological evaluation and DSI of the brain. We performed voxel-based GFA analysis for global white matter evaluation, tractography-based analysis for tract-to-tract comparisons, and tract-specific analysis of the CST to evaluate microstructural integrity along the axonal direction. | en_US |
| dc.format.extent | 2158937 bytes | - |
| dc.format.mimetype | application/pdf | - |
| dc.relation (關聯) | American Journal of Nuclear Radiology, Vol.34, No.5, pp.990-996 | en_US |
| dc.title (題名) | Microstructural integrity of cerebral fiber tracts in hereditary spastic paraparesis with SPG11 mutation. | en_US |
| dc.type (資料類型) | article | |
| dc.identifier.doi (DOI) | 10.3174/ajnr.A3330 | |
| dc.doi.uri (DOI) | https://doi.org/10.3174/ajnr.A3330 | |
