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題名 Extracellular calcium concentration and channel activity involved in aminoglycoside-induced hair cell toxicity in the zebrafish lateral line
作者 詹銘煥
CHAN, MING-HUAN
Wu, C.Y.
Liu, C.F.
Chen, H.H.
貢獻者 神科所
日期 2016-10
上傳時間 23-Nov-2017 16:56:09 (UTC+8)
摘要 Introduction: Ototoxic damage often caused by antibiotic aminoglycosides leads to the loss of hair cells. Since aminoglycosides are effective at infection treatment, it is imperative to discover new approach to prevent hearing loss and permit safe use of aminoglycosides. The alterations in cytosolic calcium homeostasis play an important role in aminoglycoside-induced sensory hair cell death. However, the involvement of cytoplasmic membrane calcium channels in aminoglycoside ototoxicity is not clear.
關聯 Toxicology Letters, Volume 259, Supplement, Page S202
資料類型 article
DOI https://doi.org/10.1016/j.toxlet.2016.07.484
dc.contributor 神科所zh_TW
dc.creator (作者) 詹銘煥zh_TW
dc.creator (作者) CHAN, MING-HUANen_US
dc.creator (作者) Wu, C.Y.en_US
dc.creator (作者) Liu, C.F.en_US
dc.creator (作者) Chen, H.H.en_US
dc.date (日期) 2016-10
dc.date.accessioned 23-Nov-2017 16:56:09 (UTC+8)-
dc.date.available 23-Nov-2017 16:56:09 (UTC+8)-
dc.date.issued (上傳時間) 23-Nov-2017 16:56:09 (UTC+8)-
dc.identifier.uri (URI) http://nccur.lib.nccu.edu.tw/handle/140.119/114861-
dc.description.abstract (摘要) Introduction: Ototoxic damage often caused by antibiotic aminoglycosides leads to the loss of hair cells. Since aminoglycosides are effective at infection treatment, it is imperative to discover new approach to prevent hearing loss and permit safe use of aminoglycosides. The alterations in cytosolic calcium homeostasis play an important role in aminoglycoside-induced sensory hair cell death. However, the involvement of cytoplasmic membrane calcium channels in aminoglycoside ototoxicity is not clear.en_US
dc.format.extent 53872 bytes-
dc.format.mimetype application/pdf-
dc.relation (關聯) Toxicology Letters, Volume 259, Supplement, Page S202en_US
dc.title (題名) Extracellular calcium concentration and channel activity involved in aminoglycoside-induced hair cell toxicity in the zebrafish lateral lineen_US
dc.type (資料類型) article
dc.identifier.doi (DOI) 10.1016/j.toxlet.2016.07.484
dc.doi.uri (DOI) https://doi.org/10.1016/j.toxlet.2016.07.484