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題名 Prevention of mother-to-child transmission: the key of hepatitis B virus elimination
作者 林志陵
Lin, Chih-Lin
Kao, Jia-Horng
貢獻者 心理系
日期 2018-03
上傳時間 18-Sep-2018 15:54:50 (UTC+8)
摘要 More than half a century after the initial discovery, hepatitis B virus (HBV) is one of the most common viral infections in humans. With a global heterogeneous prevalence, the HBV epidemic remains a monumental threat of health. In Asia, most HBV patients acquire the virus perinatally or in early childhood and develop a life-long chronic infection [1]. The mechanisms of vertical HBV transmission include intrauterine infection and transmission during delivery [2]. For example, the prevalence of chronic HBV infection in the general population ranged 11–20% in Taiwan during 1980s [3]. Approximately, 40% of HBV carriers were born to HBsAg-positive mothers and 85–95% of newborns with HBV exposure consequently had chronic infection [4]. Thus, mother-to-child transmission (MTCT) during the perinatal period is the major transmission route of HBV in hyperendemic areas [1]. Prevention of MTCT is thus the most important strategy to reduce the global burden of HBV infection.
關聯 Hepatology International, Volume 12, Issue 2, pp 94–96
資料類型 article
DOI https://doi.org/10.1007/s12072-018-9863-0
dc.contributor 心理系
dc.creator (作者) 林志陵zh_TW
dc.creator (作者) Lin, Chih-Linen_US
dc.creator (作者) Kao, Jia-Horngen_US
dc.date (日期) 2018-03
dc.date.accessioned 18-Sep-2018 15:54:50 (UTC+8)-
dc.date.available 18-Sep-2018 15:54:50 (UTC+8)-
dc.date.issued (上傳時間) 18-Sep-2018 15:54:50 (UTC+8)-
dc.identifier.uri (URI) http://nccur.lib.nccu.edu.tw/handle/140.119/120103-
dc.description.abstract (摘要) More than half a century after the initial discovery, hepatitis B virus (HBV) is one of the most common viral infections in humans. With a global heterogeneous prevalence, the HBV epidemic remains a monumental threat of health. In Asia, most HBV patients acquire the virus perinatally or in early childhood and develop a life-long chronic infection [1]. The mechanisms of vertical HBV transmission include intrauterine infection and transmission during delivery [2]. For example, the prevalence of chronic HBV infection in the general population ranged 11–20% in Taiwan during 1980s [3]. Approximately, 40% of HBV carriers were born to HBsAg-positive mothers and 85–95% of newborns with HBV exposure consequently had chronic infection [4]. Thus, mother-to-child transmission (MTCT) during the perinatal period is the major transmission route of HBV in hyperendemic areas [1]. Prevention of MTCT is thus the most important strategy to reduce the global burden of HBV infection.en_US
dc.format.extent 417674 bytes-
dc.format.mimetype application/pdf-
dc.relation (關聯) Hepatology International, Volume 12, Issue 2, pp 94–96
dc.title (題名) Prevention of mother-to-child transmission: the key of hepatitis B virus eliminationen_US
dc.type (資料類型) article
dc.identifier.doi (DOI) 10.1007/s12072-018-9863-0
dc.doi.uri (DOI) https://doi.org/10.1007/s12072-018-9863-0