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題名 AFFECT: an R package for accelerated functional failure time model with error-contaminated survival times and applications to gene expression data
作者 陳立榜
Chen, Li-Pang;Huang, Hsiao-Ting
貢獻者 統計系
關鍵詞 Boosting; Gene expression; Measurement error; Survival analysis
日期 2024-08
上傳時間 28-Oct-2024 11:42:47 (UTC+8)
摘要 Survival analysis has been used to characterize the time-to-event data. In medical studies, a typical application is to analyze the survival time of specific cancers by using high-dimensional gene expressions. The main challenges include the involvement of non-informaive gene expressions and possibly nonlinear relationship between survival time and gene expressions. Moreover, due to possibly imprecise data collection or wrong record, measurement error might be ubiquitous in the survival time and its censoring status. Ignoring measurement error effects may incur biased estimator and wrong conclusion.
關聯 BMC Bioinformatics, Vol.25, Article number: 265, pp.1-20
資料類型 article
DOI https://doi.org/10.1186/s12859-024-05831-5
dc.contributor 統計系
dc.creator (作者) 陳立榜
dc.creator (作者) Chen, Li-Pang;Huang, Hsiao-Ting
dc.date (日期) 2024-08
dc.date.accessioned 28-Oct-2024 11:42:47 (UTC+8)-
dc.date.available 28-Oct-2024 11:42:47 (UTC+8)-
dc.date.issued (上傳時間) 28-Oct-2024 11:42:47 (UTC+8)-
dc.identifier.uri (URI) https://nccur.lib.nccu.edu.tw/handle/140.119/154113-
dc.description.abstract (摘要) Survival analysis has been used to characterize the time-to-event data. In medical studies, a typical application is to analyze the survival time of specific cancers by using high-dimensional gene expressions. The main challenges include the involvement of non-informaive gene expressions and possibly nonlinear relationship between survival time and gene expressions. Moreover, due to possibly imprecise data collection or wrong record, measurement error might be ubiquitous in the survival time and its censoring status. Ignoring measurement error effects may incur biased estimator and wrong conclusion.
dc.format.extent 106 bytes-
dc.format.mimetype text/html-
dc.relation (關聯) BMC Bioinformatics, Vol.25, Article number: 265, pp.1-20
dc.subject (關鍵詞) Boosting; Gene expression; Measurement error; Survival analysis
dc.title (題名) AFFECT: an R package for accelerated functional failure time model with error-contaminated survival times and applications to gene expression data
dc.type (資料類型) article
dc.identifier.doi (DOI) 10.1186/s12859-024-05831-5
dc.doi.uri (DOI) https://doi.org/10.1186/s12859-024-05831-5