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題名 Exercise prevents hypertension and disrupts the correlation between vascular sympathetic activity and age-related increase in blood pressure in SHRs
作者 陳玠文
Chen, Chieh-Wen;Li, Jia-Yi;Liu, Tsung-Han;Kuo, Terry Bj;Yang, Cheryl Ch
貢獻者 神科所
關鍵詞 blood pressure; established hypertension; hypertension; sleep pattern; spontaneously hypertensive rat; sympathetic nervous system; treadmill exercise
日期 2019-11
上傳時間 13-Jun-2025 09:25:24 (UTC+8)
摘要 Background: Hypertension usually accompanies the elevated sympathetic activity and sleep interruption. Few researches explored the dynamic changes and possible correlations in cardiovascular functions and sleep patterns during the development of hypertension. In contrast, exercise training provides several benefits on cardiovascular and sleep function in hypertensive subjects. However, controlling various factors during a long period of exercise training is difficult in hypertensive subjects, an animal model may be essential. This study aimed to explore dynamic changes in cardiovascular functions and sleep patterns during the development period of hypertension (10–20 weeks old) in spontaneously hypertensive rats (SHRs) and effects of exercise intervention.
關聯 American Journal of Hypertension, Vol.32, No.11, pp.1091-1100
資料類型 article
DOI https://doi.org/10.1093/ajh/hpz115
dc.contributor 神科所
dc.creator (作者) 陳玠文
dc.creator (作者) Chen, Chieh-Wen;Li, Jia-Yi;Liu, Tsung-Han;Kuo, Terry Bj;Yang, Cheryl Ch
dc.date (日期) 2019-11
dc.date.accessioned 13-Jun-2025 09:25:24 (UTC+8)-
dc.date.available 13-Jun-2025 09:25:24 (UTC+8)-
dc.date.issued (上傳時間) 13-Jun-2025 09:25:24 (UTC+8)-
dc.identifier.uri (URI) https://nccur.lib.nccu.edu.tw/handle/140.119/157330-
dc.description.abstract (摘要) Background: Hypertension usually accompanies the elevated sympathetic activity and sleep interruption. Few researches explored the dynamic changes and possible correlations in cardiovascular functions and sleep patterns during the development of hypertension. In contrast, exercise training provides several benefits on cardiovascular and sleep function in hypertensive subjects. However, controlling various factors during a long period of exercise training is difficult in hypertensive subjects, an animal model may be essential. This study aimed to explore dynamic changes in cardiovascular functions and sleep patterns during the development period of hypertension (10–20 weeks old) in spontaneously hypertensive rats (SHRs) and effects of exercise intervention.
dc.format.extent 98 bytes-
dc.format.mimetype text/html-
dc.relation (關聯) American Journal of Hypertension, Vol.32, No.11, pp.1091-1100
dc.subject (關鍵詞) blood pressure; established hypertension; hypertension; sleep pattern; spontaneously hypertensive rat; sympathetic nervous system; treadmill exercise
dc.title (題名) Exercise prevents hypertension and disrupts the correlation between vascular sympathetic activity and age-related increase in blood pressure in SHRs
dc.type (資料類型) article
dc.identifier.doi (DOI) 10.1093/ajh/hpz115
dc.doi.uri (DOI) https://doi.org/10.1093/ajh/hpz115