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題名 Distinct temporal patterns of acute intermittent hypoxia differentially affect sleep, autonomic regulation, and cognition in normotensive and hypertensive rats
作者 陳玠文
She, Sheng-Chieh;Lin, Chi-Wei;Chen, Chieh-Wen;al, et
貢獻者 神科所
關鍵詞 Intermittent hypoxia; Hypoxic patterning; Autonomic regulation; Sleep structure; Blood pressure; Baroreflex
日期 2026-08
上傳時間 7-May-2026 10:32:43 (UTC+8)
摘要 Background: Intermittent hypoxia (IH) is a defining physiological component of obstructive sleep apnea (OSA), yet clinical outcomes vary considerably among individuals with similar event frequencies. We investigated whether distinct temporal structures of IH—defined by hypoxic duration and cycling frequency—differentially affect sleep and autonomic regulation, and whether hypertensive status modifies vulnerability.
關聯 Sleep Medicine, Vol.144, 108939
資料類型 article
DOI https://doi.org/10.1016/j.sleep.2026.108939
dc.contributor 神科所
dc.creator (作者) 陳玠文
dc.creator (作者) She, Sheng-Chieh;Lin, Chi-Wei;Chen, Chieh-Wen;al, et
dc.date (日期) 2026-08
dc.date.accessioned 7-May-2026 10:32:43 (UTC+8)-
dc.date.available 7-May-2026 10:32:43 (UTC+8)-
dc.date.issued (上傳時間) 7-May-2026 10:32:43 (UTC+8)-
dc.identifier.uri (URI) https://ah.lib.nccu.edu.tw/item?item_id=182357-
dc.description.abstract (摘要) Background: Intermittent hypoxia (IH) is a defining physiological component of obstructive sleep apnea (OSA), yet clinical outcomes vary considerably among individuals with similar event frequencies. We investigated whether distinct temporal structures of IH—defined by hypoxic duration and cycling frequency—differentially affect sleep and autonomic regulation, and whether hypertensive status modifies vulnerability.
dc.format.extent 107 bytes-
dc.format.mimetype text/html-
dc.relation (關聯) Sleep Medicine, Vol.144, 108939
dc.subject (關鍵詞) Intermittent hypoxia; Hypoxic patterning; Autonomic regulation; Sleep structure; Blood pressure; Baroreflex
dc.title (題名) Distinct temporal patterns of acute intermittent hypoxia differentially affect sleep, autonomic regulation, and cognition in normotensive and hypertensive rats
dc.type (資料類型) article
dc.identifier.doi (DOI) 10.1016/j.sleep.2026.108939
dc.doi.uri (DOI) https://doi.org/10.1016/j.sleep.2026.108939