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題名 Multiclassification for high-dimensional error-prone gene expression data 作者 陳立榜
Chen, Li-Pang貢獻者 統計系 日期 2026-06 上傳時間 2026-05-14 摘要 In supervised learning, linear discriminant analysis is a well-known classification method. Its conventional implementation relies on precisely measured variables and the computation of the inverse covariance matrix, commonly referred to as the precision matrix. However, this setting may be unrealistic for gene expression data due to several inherent challenges, including measurement error, network dependence, and high dimensionality. To address these challenges and provide reliable classification, we propose a new method, termed GUEST, which is designed to perform graphical estimation for ultrahigh-dimensional and error-prone gene expression data via a boosting algorithm. With the precision matrix properly estimated, the resulting estimator can be used to construct the linear discriminant function, and empirical results demonstrate a substantial improvement in classification accuracy. 關聯 The Annual Meeting of the Classification Society, The Classification Society 資料類型 conference dc.contributor 統計系 dc.creator (作者) 陳立榜 dc.creator (作者) Chen, Li-Pang dc.date (日期) 2026-06 dc.date.accessioned 2026-05-14 - dc.date.available 2026-05-14 - dc.date.issued (上傳時間) 2026-05-14 - dc.identifier.uri (URI) https://ah.lib.nccu.edu.tw/item?item_id=182573 - dc.description.abstract (摘要) In supervised learning, linear discriminant analysis is a well-known classification method. Its conventional implementation relies on precisely measured variables and the computation of the inverse covariance matrix, commonly referred to as the precision matrix. However, this setting may be unrealistic for gene expression data due to several inherent challenges, including measurement error, network dependence, and high dimensionality. To address these challenges and provide reliable classification, we propose a new method, termed GUEST, which is designed to perform graphical estimation for ultrahigh-dimensional and error-prone gene expression data via a boosting algorithm. With the precision matrix properly estimated, the resulting estimator can be used to construct the linear discriminant function, and empirical results demonstrate a substantial improvement in classification accuracy. dc.format.extent 95455 bytes - dc.format.mimetype application/pdf - dc.relation (關聯) The Annual Meeting of the Classification Society, The Classification Society dc.title (題名) Multiclassification for high-dimensional error-prone gene expression data dc.type (資料類型) conference
