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題名 Testing the Nonrandomness of Choromosomal Breakpoints Using Highest Observed Breakages
作者 侯家鼎;江振東;戴政
Hou, Chia-Ding;Chiang, Jengtung;John Jen Tai
日期 1999-04
上傳時間 19-Dec-2008 14:52:27 (UTC+8)
摘要 To determine whether a chromosomal band is a fragile site rather than a spontaneous breakpoint, an essential step is to test the nonrandomness of breakage at the region. In this paper, the nonapplicability of the testing procedure introduced by Bohm et al. is discussed, and a new detection procedure is proposed. This new procedure considers the relations of one site with the others, and can be applied to tests of the nonrandomness of breakpoints under either the proportional probability model, or the equiprobability model. A data set for Chinese patients with colorectal carcinoma is analyzed as an illustration of the proposed method.
關聯 Human Genetics, 104(4), 350-355
資料類型 article
DOI http://dx.doi.org/10.1007/s004390050965
dc.creator (作者) 侯家鼎;江振東;戴政zh_TW
dc.creator (作者) Hou, Chia-Ding;Chiang, Jengtung;John Jen Tai-
dc.date (日期) 1999-04en_US
dc.date.accessioned 19-Dec-2008 14:52:27 (UTC+8)-
dc.date.available 19-Dec-2008 14:52:27 (UTC+8)-
dc.date.issued (上傳時間) 19-Dec-2008 14:52:27 (UTC+8)-
dc.identifier.uri (URI) https://nccur.lib.nccu.edu.tw/handle/140.119/18168-
dc.description.abstract (摘要) To determine whether a chromosomal band is a fragile site rather than a spontaneous breakpoint, an essential step is to test the nonrandomness of breakage at the region. In this paper, the nonapplicability of the testing procedure introduced by Bohm et al. is discussed, and a new detection procedure is proposed. This new procedure considers the relations of one site with the others, and can be applied to tests of the nonrandomness of breakpoints under either the proportional probability model, or the equiprobability model. A data set for Chinese patients with colorectal carcinoma is analyzed as an illustration of the proposed method.-
dc.format application/en_US
dc.language enen_US
dc.language en-USen_US
dc.language.iso en_US-
dc.relation (關聯) Human Genetics, 104(4), 350-355en_US
dc.title (題名) Testing the Nonrandomness of Choromosomal Breakpoints Using Highest Observed Breakagesen_US
dc.type (資料類型) articleen
dc.identifier.doi (DOI) 10.1007/s004390050965en_US
dc.doi.uri (DOI) http://dx.doi.org/10.1007/s004390050965en_US