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題名 ERP Evidence of Enhanced Excitatory and Reduced Inhibitory Processes of Auditory Stimuli during Sleep in Patients with Primary Insomnia
作者 Lo, H.S
Yang, C.M
楊建銘
關鍵詞 ERP;Insomnia; Information Procesing
日期 2007
上傳時間 31-Dec-2008 11:18:53 (UTC+8)
摘要 Study Objectives:
     
     Increased information processing around the onset of sleep and during sleep has been suggested as an important factor for the pathogenesis of insomnia. The purpose of the present study was to examine the processing of auditory information during sleep in patients with insomnia through the recording of event-related potentials (ERPs).
     
     Design:
     
     A mixed design was used in which subject group was a between subject factor and sleep stage and type of tone presented were within subject factors.
     
     Participants:
     
     Fifteen patients with primary insomnia and 15 normal sleepers
     (controls) were studied.
     
     Measurements and Results:
     
     An odd-ball paradigm was conducted to evoke ERPs throughout the night. Patients with insomnia showed larger N1 and smaller P2 to rare tones, smaller N350 to standard tones, and slower P900 to both tones during the first 5 minutes of continuous stage 2 sleep. No consistent ERP differences were detected between the 2 groups when the waveforms were averaged across the whole night.
     
     Conclusions:
     
     Patients with insomnia showed an enhancement in attention and a reduction in the inhibitory process that normally facilitates sleep onset in the beginning part of sleep. The results partially support the hyperarousal theory, ie, enhanced information processing during the initiation of sleep is a contributing factor for insomnia.
關聯 Sleep, 30(5), 585-592
資料類型 article
dc.creator (作者) Lo, H.Sen_US
dc.creator (作者) Yang, C.Men_US
dc.creator (作者) 楊建銘zh_TW
dc.date (日期) 2007en_US
dc.date.accessioned 31-Dec-2008 11:18:53 (UTC+8)-
dc.date.available 31-Dec-2008 11:18:53 (UTC+8)-
dc.date.issued (上傳時間) 31-Dec-2008 11:18:53 (UTC+8)-
dc.identifier.uri (URI) https://nccur.lib.nccu.edu.tw/handle/140.119/21220-
dc.description.abstract (摘要) Study Objectives:
     
     Increased information processing around the onset of sleep and during sleep has been suggested as an important factor for the pathogenesis of insomnia. The purpose of the present study was to examine the processing of auditory information during sleep in patients with insomnia through the recording of event-related potentials (ERPs).
     
     Design:
     
     A mixed design was used in which subject group was a between subject factor and sleep stage and type of tone presented were within subject factors.
     
     Participants:
     
     Fifteen patients with primary insomnia and 15 normal sleepers
     (controls) were studied.
     
     Measurements and Results:
     
     An odd-ball paradigm was conducted to evoke ERPs throughout the night. Patients with insomnia showed larger N1 and smaller P2 to rare tones, smaller N350 to standard tones, and slower P900 to both tones during the first 5 minutes of continuous stage 2 sleep. No consistent ERP differences were detected between the 2 groups when the waveforms were averaged across the whole night.
     
     Conclusions:
     
     Patients with insomnia showed an enhancement in attention and a reduction in the inhibitory process that normally facilitates sleep onset in the beginning part of sleep. The results partially support the hyperarousal theory, ie, enhanced information processing during the initiation of sleep is a contributing factor for insomnia.
-
dc.format application/en_US
dc.language enen_US
dc.language en-USen_US
dc.language.iso en_US-
dc.relation (關聯) Sleep, 30(5), 585-592en_US
dc.subject (關鍵詞) ERP;Insomnia; Information Procesing-
dc.title (題名) ERP Evidence of Enhanced Excitatory and Reduced Inhibitory Processes of Auditory Stimuli during Sleep in Patients with Primary Insomniaen_US
dc.type (資料類型) articleen