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題名 Photothermal cancer therapy via femtosecond-laser-excited FePt nanoparticles
作者 陳洋元
Chen,Cheng-Lung ; Kuo,Ling-Ru ; Lee,Shin-Yu ; Hwu,Yeu-Kuang ; Chou,Shang-Wei ; Chen,Chia-Chun ; Chang,Fu-Hsiung ; Lin,Kung-Hsuan ; Tsai,Dzung-Han ; Chen,Yang-Yuan
貢獻者 應物所
關鍵詞 Photothermal therapy; FePt; Nanoparticle; Cancer therapy; Thermal lens; Laser
日期 2013.01
上傳時間 11-Nov-2013 09:37:47 (UTC+8)
摘要 FePt nanoparticles (NPs) have recently been revealed to be significant multifunctional materials for the applications of biomedical imaging, drug delivery and magnetic hyperthermia due to their novel magnetic properties. In this study, a newly discovered photothermal effect activated by the near infrared (NIR) femtosecond laser for FePt NPs was demonstrated. The threshold laser energy to destroy cancer cells was found to be comparable to that of gold nanorods (Au NRs) previously reported. Through the thermal lens technique, it was concluded that the temperature of the FePt NPs can be heated up to a couple of hundreds degree C in picoseconds under laser irradiation due to the excellent photothermal transduction efficiency of FePt NPs. This finding boosts FePt NPs versatility in multifunctional targeted cancer therapy.
關聯 Biomaterials, 34(4), 1128-1134
資料類型 article
DOI http://dx.doi.org/10.1016/j.biomaterials.2012.10.044
dc.contributor 應物所en_US
dc.creator (作者) 陳洋元zh_TW
dc.creator (作者) Chen,Cheng-Lung ; Kuo,Ling-Ru ; Lee,Shin-Yu ; Hwu,Yeu-Kuang ; Chou,Shang-Wei ; Chen,Chia-Chun ; Chang,Fu-Hsiung ; Lin,Kung-Hsuan ; Tsai,Dzung-Han ; Chen,Yang-Yuanen_US
dc.date (日期) 2013.01en_US
dc.date.accessioned 11-Nov-2013 09:37:47 (UTC+8)-
dc.date.available 11-Nov-2013 09:37:47 (UTC+8)-
dc.date.issued (上傳時間) 11-Nov-2013 09:37:47 (UTC+8)-
dc.identifier.uri (URI) http://nccur.lib.nccu.edu.tw/handle/140.119/61552-
dc.description.abstract (摘要) FePt nanoparticles (NPs) have recently been revealed to be significant multifunctional materials for the applications of biomedical imaging, drug delivery and magnetic hyperthermia due to their novel magnetic properties. In this study, a newly discovered photothermal effect activated by the near infrared (NIR) femtosecond laser for FePt NPs was demonstrated. The threshold laser energy to destroy cancer cells was found to be comparable to that of gold nanorods (Au NRs) previously reported. Through the thermal lens technique, it was concluded that the temperature of the FePt NPs can be heated up to a couple of hundreds degree C in picoseconds under laser irradiation due to the excellent photothermal transduction efficiency of FePt NPs. This finding boosts FePt NPs versatility in multifunctional targeted cancer therapy.en_US
dc.format.extent 1407338 bytes-
dc.format.mimetype application/pdf-
dc.language.iso en_US-
dc.relation (關聯) Biomaterials, 34(4), 1128-1134en_US
dc.subject (關鍵詞) Photothermal therapy; FePt; Nanoparticle; Cancer therapy; Thermal lens; Laseren_US
dc.title (題名) Photothermal cancer therapy via femtosecond-laser-excited FePt nanoparticlesen_US
dc.type (資料類型) articleen
dc.identifier.doi (DOI) 10.1016/j.biomaterials.2012.10.044en_US
dc.doi.uri (DOI) http://dx.doi.org/10.1016/j.biomaterials.2012.10.044en_US