| dc.contributor | 應物所 | en_US |
| dc.creator (作者) | 蔡尚岳 | zh_TW |
| dc.creator (作者) | Tsai, Shang-Yueh ; Otazo, Ricardo ; Posse, Stefan ; Lin, Yi-Ru ; Chung, Hsiao-Wen ; Wald, Lawrence L. ; Wiggins, Graham C. ; Lin, Fa-Hsuan | en_US |
| dc.date (日期) | 2008.04 | en_US |
| dc.date.accessioned | 11-Feb-2014 14:02:20 (UTC+8) | - |
| dc.date.available | 11-Feb-2014 14:02:20 (UTC+8) | - |
| dc.date.issued (上傳時間) | 11-Feb-2014 14:02:20 (UTC+8) | - |
| dc.identifier.uri (URI) | http://nccur.lib.nccu.edu.tw/handle/140.119/63785 | - |
| dc.description.abstract (摘要) | Parallel imaging has been demonstrated to reduce the encoding time of MR spectroscopic imaging (MRSI). Here we investigate up to 5-fold acceleration of 2D proton echo planar spectroscopic imaging (PEPSI) at 3T using generalized autocalibrating partial parallel acquisition (GRAPPA) with a 32-channel coil array, 1.5 cm3 voxel size, TR/TE of 15/2000 ms, and 2.1 Hz spectral resolution. Compared to an 8-channel array, the smaller RF coil elements in this 32-channel array provided a 3.1-fold and 2.8-fold increase in signal-to-noise ratio (SNR) in the peripheral region and the central region, respectively, and more spatial modulated information. Comparison of sensitivity-encoding (SENSE) and GRAPPA reconstruction using an 8-channel array showed that both methods yielded similar quantitative metabolite measures (P > 0.1). Concentration values of N-acetyl-aspartate (NAA), total creatine (tCr), choline (Cho), myo-inositol (mI), and the sum of glutamate and glutamine (Glx) for both methods were consistent with previous studies. Using the 32-channel array coil the mean Cramer–Rao lower bounds (CRLB) were less than 8% for NAA, tCr, and Cho and less than 15% for mI and Glx at 2-fold acceleration. At 4-fold acceleration the mean CRLB for NAA, tCr, and Cho was less than 11%. In conclusion, the use of a 32-channel coil array and GRAPPA reconstruction can significantly reduce the measurement time for mapping brain metabolites. Magn Reson Med 59:989–998, 2008. © 2008 Wiley-Liss, Inc. | en_US |
| dc.format.extent | 1150044 bytes | - |
| dc.format.mimetype | application/pdf | - |
| dc.language.iso | en_US | - |
| dc.relation (關聯) | Magn Reson Med, 59(5), 989-998 | en_US |
| dc.subject (關鍵詞) | proton echo planar spectroscopic imaging; PEPSI; MR spectroscopic imaging; parallel MRI; 32 | en_US |
| dc.title (題名) | Accelerated Proton-Echo-Planar-Spectroscopic-Imaging using GRAPPA with a 32-Channel Phase Array Coil | en_US |
| dc.type (資料類型) | article | en |
