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題名 An expedient synthesis of honokiol and its analogues as potential neuropreventive agents
作者 Tripathi, Subhankar ; Chan, Ming-Huan ; Chen, Chinpiao
詹銘煥
貢獻者 神科所
關鍵詞 Honokiol; Neuropreventive; Parkinson’s disease; Suzuki–Miyaura cross coupling; Claisen rearrangement
日期 2012.01
上傳時間 9-Apr-2014 17:17:29 (UTC+8)
摘要 An efficient synthesis of honokiol with Suzuki–Miyaura cross coupling obtained an overall yield of 45%. The proposed approach successfully synthesized several structurally similar alkyl, alkenyl and alkynyl analogues, seven of which showed potential neuropreventive activity against MPP+-induced and CHP/TBHP oxidative stress induced neuroblastoma cell death.
關聯 Bioorg Med Chem Lett,22(1), 216-221
資料來源 http://dx.doi.org/10.1016/j.bmcl.2011.11.030
資料類型 article
dc.contributor 神科所en_US
dc.creator (作者) Tripathi, Subhankar ; Chan, Ming-Huan ; Chen, Chinpiaoen_US
dc.creator (作者) 詹銘煥zh_TW
dc.date (日期) 2012.01en_US
dc.date.accessioned 9-Apr-2014 17:17:29 (UTC+8)-
dc.date.available 9-Apr-2014 17:17:29 (UTC+8)-
dc.date.issued (上傳時間) 9-Apr-2014 17:17:29 (UTC+8)-
dc.identifier.uri (URI) http://nccur.lib.nccu.edu.tw/handle/140.119/65229-
dc.description.abstract (摘要) An efficient synthesis of honokiol with Suzuki–Miyaura cross coupling obtained an overall yield of 45%. The proposed approach successfully synthesized several structurally similar alkyl, alkenyl and alkynyl analogues, seven of which showed potential neuropreventive activity against MPP+-induced and CHP/TBHP oxidative stress induced neuroblastoma cell death.en_US
dc.format.extent 580915 bytes-
dc.format.mimetype application/pdf-
dc.language.iso en_US-
dc.relation (關聯) Bioorg Med Chem Lett,22(1), 216-221en_US
dc.source.uri (資料來源) http://dx.doi.org/10.1016/j.bmcl.2011.11.030en_US
dc.subject (關鍵詞) Honokiol; Neuropreventive; Parkinson’s disease; Suzuki–Miyaura cross coupling; Claisen rearrangementen_US
dc.title (題名) An expedient synthesis of honokiol and its analogues as potential neuropreventive agentsen_US
dc.type (資料類型) articleen