| dc.contributor | 應物所 | en_US |
| dc.creator (作者) | 蔡尚岳 | zh_TW |
| dc.creator (作者) | Tsai,Shang-Yueh ;Wu,Ming-Ting;Lin,Yi-Ru;Hsieh,Kai-Sheng;Lin,Chu-Chuan;Huang,Teng-Yi | en_US |
| dc.date (日期) | 2006.08 | en_US |
| dc.date.accessioned | 1-May-2014 17:47:06 (UTC+8) | - |
| dc.date.available | 1-May-2014 17:47:06 (UTC+8) | - |
| dc.date.issued (上傳時間) | 1-May-2014 17:47:06 (UTC+8) | - |
| dc.identifier.uri (URI) | http://nccur.lib.nccu.edu.tw/handle/140.119/65800 | - |
| dc.description.abstract (摘要) | A temporal correlation (TC) mapping method is proposed to help bolus chasing during dynamic contrast-enhanced (DCE) MRI of complex pulmonary circulation (CPC) in patients with congenital heart disease. DCE-MRI was performed on five healthy male subjects (23–24 years old) and 25 patients (nine males and 16 females, 0.25–44 years old), and TC maps were generated by performing pixel-based computation of cross-correlations to the pulmonary artery with a series of time shifts in all subjects. Qualitative and quantitative evaluations were performed in comparison with original DCE images. TC maps exhibited a better signal-to-noise ratio (SNR) by factors of 4.3 and 1.3 in the lung parenchyma, pulmonary veins, and superior artery/vein; a better intraparenchymal contrast-to-noise ratio (CNR) by factors of 1.5–5.4; and a significantly higher conspicuity in all regions except the pulmonary arteries when graded with a five-point score. TC maps evaluated by two experienced clinicians significantly added relevant information (P < 0.001), and in some cases affected the final diagnosis. We conclude that TC maps facilitate bolus chasing for DCE-MRI by reducing recirculation effects and interframe fluctuations, and hence complements morphological imaging of CPC in patients with complex congenital heart disease. Magn Reson Med, 2006. © 2006 Wiley-Liss, Inc. | en_US |
| dc.format.extent | 1004921 bytes | - |
| dc.format.mimetype | application/pdf | - |
| dc.language.iso | en_US | - |
| dc.relation (關聯) | Magn Reson Med, 56(3), 517-526 | en_US |
| dc.subject (關鍵詞) | congenital heart disease;contrast-enhanced MRI;cross-correlation analysis;pulmonary circulation;temporal correlation map | en_US |
| dc.title (題名) | Temporal correlation-based dynamic contrast-enhanced MR imaging improves assessment of complex pulmonary circulation in congenital heart disease | en_US |
| dc.type (資料類型) | article | en |
