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題名 Stimulated echo induced misestimates on diffusion tensor indices and its remedy
作者 蔡尚岳
Tsai, Shang-Yueh ; Chuang,Tzu-Chao;Wu,Ming-Ting;Huang,Teng-Yi;Lin,Yi-Ru ; Chang, Hing-Chiu
貢獻者 應物所
關鍵詞 diffusion-weighted imaging;eddy current;twice-refocused spin-echo;stimulated echo;apparent diffusion coefficient;fractional anisotropy
日期 2010.05
上傳時間 1-May-2014 17:54:05 (UTC+8)
摘要 diffusion-weighted imaging;eddy current;twice-refocused spin-echo;stimulated echo;apparent diffusion coefficient;fractional anisotropy
PURPOSE: To report possible erroneous estimates of diffusion parameters in the twice-refocused spin-echo (TRSE) technique, proposed to eliminate eddy-current-induced geometric distortions in diffusion-weighted echo-planar imaging, when stimulated echo signals are inappropriately included. MATERIALS AND METHODS: Eleven subjects were included for imaging experiments on two 1.5 Tesla systems using the TRSE sequence. Three versions, two with unbalanced crusher gradients inserted to dephase the stimulated echo from the b = 0 images and one with balanced crusher gradients, were implemented. The apparent diffusion coefficients (ADC) and fractional anisotropy (FA) were derived and compared. RESULTS: The ADCs obtained with unbalanced crusher gradients were closer to values reported in the literature. Stimulated echo led to ADC over-estimations by 34.2%, 50.4%, 54.0%, 51.5%, 24.0%, and 41.9% in the genu of corpus callosum, splenium of corpus callosum, bilateral corona radiata, internal capsule, mediofrontal gyrus, and the cuneus, respectively (P < 0.01), with concomitant reduction in FA in highly anisotropic regions. Over-estimations of diffusion coefficients were found to be roughly equal along all directions. CONCLUSION: Formation of stimulated echo in the TRSE technique can lead to erroneous estimations of the diffusion parameters, even if no prominent morphological artifacts are seen.
關聯 J Magn Reson Imaging, 31(6), 1522-1529
資料類型 article
dc.contributor 應物所en_US
dc.creator (作者) 蔡尚岳zh_TW
dc.creator (作者) Tsai, Shang-Yueh ; Chuang,Tzu-Chao;Wu,Ming-Ting;Huang,Teng-Yi;Lin,Yi-Ru ; Chang, Hing-Chiuen_US
dc.date (日期) 2010.05en_US
dc.date.accessioned 1-May-2014 17:54:05 (UTC+8)-
dc.date.available 1-May-2014 17:54:05 (UTC+8)-
dc.date.issued (上傳時間) 1-May-2014 17:54:05 (UTC+8)-
dc.identifier.uri (URI) http://nccur.lib.nccu.edu.tw/handle/140.119/65811-
dc.description.abstract (摘要) diffusion-weighted imaging;eddy current;twice-refocused spin-echo;stimulated echo;apparent diffusion coefficient;fractional anisotropyen_US
dc.description.abstract (摘要) PURPOSE: To report possible erroneous estimates of diffusion parameters in the twice-refocused spin-echo (TRSE) technique, proposed to eliminate eddy-current-induced geometric distortions in diffusion-weighted echo-planar imaging, when stimulated echo signals are inappropriately included. MATERIALS AND METHODS: Eleven subjects were included for imaging experiments on two 1.5 Tesla systems using the TRSE sequence. Three versions, two with unbalanced crusher gradients inserted to dephase the stimulated echo from the b = 0 images and one with balanced crusher gradients, were implemented. The apparent diffusion coefficients (ADC) and fractional anisotropy (FA) were derived and compared. RESULTS: The ADCs obtained with unbalanced crusher gradients were closer to values reported in the literature. Stimulated echo led to ADC over-estimations by 34.2%, 50.4%, 54.0%, 51.5%, 24.0%, and 41.9% in the genu of corpus callosum, splenium of corpus callosum, bilateral corona radiata, internal capsule, mediofrontal gyrus, and the cuneus, respectively (P < 0.01), with concomitant reduction in FA in highly anisotropic regions. Over-estimations of diffusion coefficients were found to be roughly equal along all directions. CONCLUSION: Formation of stimulated echo in the TRSE technique can lead to erroneous estimations of the diffusion parameters, even if no prominent morphological artifacts are seen.-
dc.format.extent 384411 bytes-
dc.format.mimetype application/pdf-
dc.language.iso en_US-
dc.relation (關聯) J Magn Reson Imaging, 31(6), 1522-1529en_US
dc.subject (關鍵詞) diffusion-weighted imaging;eddy current;twice-refocused spin-echo;stimulated echo;apparent diffusion coefficient;fractional anisotropy-
dc.title (題名) Stimulated echo induced misestimates on diffusion tensor indices and its remedyen_US
dc.type (資料類型) articleen