| dc.contributor | 應物所 | en_US |
| dc.creator (作者) | 蔡尚岳 | zh_TW |
| dc.creator (作者) | Tsai, Shang-Yueh | en_US |
| dc.date (日期) | 2009.03 | en_US |
| dc.date.accessioned | 1-May-2014 17:54:45 (UTC+8) | - |
| dc.date.available | 1-May-2014 17:54:45 (UTC+8) | - |
| dc.date.issued (上傳時間) | 1-May-2014 17:54:45 (UTC+8) | - |
| dc.identifier.uri (URI) | http://nccur.lib.nccu.edu.tw/handle/140.119/65814 | - |
| dc.description.abstract (摘要) | A magnetic resonance spectroscopic imaging (MRSI) pulse sequence based on proton-echo-planar-spectroscopic-imaging (PEPSI) is introduced that measures two-dimensional metabolite maps in a single excitation. Echo-planar spatial-spectral encoding was combined with interleaved phase encoding and parallel imaging using SENSE to reconstruct absorption mode spectra. The symmetrical k-space trajectory compensates phase errors due to convolution of spatial and spectral encoding. Single-shot MRSI at short TE was evaluated in phantoms and in vivo on a 3-T whole-body scanner equipped with a 12-channel array coil. Four-step interleaved phase encoding and fourfold SENSE acceleration were used to encode a 16 x 16 spatial matrix with a 390-Hz spectral width. Comparison with conventional PEPSI and PEPSI with fourfold SENSE acceleration demonstrated comparable sensitivity per unit time when taking into account g-factor-related noise increases and differences in sampling efficiency. LCModel fitting enabled quantification of inositol, choline, creatine, and N-acetyl-aspartate (NAA) in vivo with concentration values in the ranges measured with conventional PEPSI and SENSE-accelerated PEPSI. Cramer-Rao lower bounds were comparable to those obtained with conventional SENSE-accelerated PEPSI at the same voxel size and measurement time. This single-shot MRSI method is therefore suitable for applications that require high temporal resolution to monitor temporal dynamics or to reduce sensitivity to tissue movement. | en_US |
| dc.format.extent | 435071 bytes | - |
| dc.format.mimetype | application/pdf | - |
| dc.language.iso | en_US | - |
| dc.relation (關聯) | J. Med. Biol. Eng., 61(3), 541-547 | en_US |
| dc.title (題名) | Single-Shot MR Spectroscopy Imaging with Partial Parallel Imaging | en_US |
| dc.type (資料類型) | article | en |
