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題名 Prescription profile of Chinese herbal products containing coumestrol, genestein, and/or daidzein among female users: an analysis of national health insurance data in Taiwan between 1997 and 2007 作者 曾正男
Tzeng,Jeng-Nan
Wang,Jung-Der
Tsan,Shun-Hua
Lai,Jung-Nien
Wu,Chien-Tung貢獻者 應數系 日期 2012 上傳時間 7-Aug-2014 11:35:36 (UTC+8) 摘要 Background:Some Chinese herbs contain several kinds of phytoestrogens, and these herbs are commonly prescribed in Taiwan. Phytoestrogens may influence the effects of estrogen in females, although their activities are weak. This study aims to identify the risk and analyze the prescription profile of commonly used phytoestrogenic herbs in Taiwan. Methods:The study analyzed women who had been prescribed phytoestrogenic herbs including coumestrol, genistein and/or daidzein between 1997 and 2007 in a fixed cohort taken from all female beneficiaries from the National Health Insurance Research Database of Taiwan. The prescription frequencies, cumulated dosages, and primary indications were listed. Results:A total of 462,861 women were included in the study, of whom ~47.0% had used phytoestrogenic herbs at least once during the study period. A total of 6,270,813 prescriptions were recorded, and more than 20% of these contained phytoestrogens. The most commonly prescribed herb and formula were Puerariae Radix and Ge gen tang (Pueraria Decoction), respectively. Most of the prescriptions were issued for diseases of the respiratory system, followed by symptoms, signs, and ill-defined conditions and diseases of the musculoskeletal system and connective tissue. Conclusion:This study shows that women who sought medical treatment from Chinese medicine doctors for relief of respiratory discomfort had a high possibility of exposure to phytoestrogenic herbs. Safety issues related to the female endocrine system should be a priority for future research. 關聯 Chinese Medicine,7:22 資料類型 article DOI http://dx.doi.org/10.1186/1749-8546-7-22 dc.contributor 應數系 en_US dc.creator (作者) 曾正男 zh_TW dc.creator (作者) Tzeng,Jeng-Nan en_US dc.creator (作者) Wang,Jung-Der en_US dc.creator (作者) Tsan,Shun-Hua en_US dc.creator (作者) Lai,Jung-Nien en_US dc.creator (作者) Wu,Chien-Tung en_US dc.date (日期) 2012 en_US dc.date.accessioned 7-Aug-2014 11:35:36 (UTC+8) - dc.date.available 7-Aug-2014 11:35:36 (UTC+8) - dc.date.issued (上傳時間) 7-Aug-2014 11:35:36 (UTC+8) - dc.identifier.uri (URI) http://nccur.lib.nccu.edu.tw/handle/140.119/68418 - dc.description.abstract (摘要) Background:Some Chinese herbs contain several kinds of phytoestrogens, and these herbs are commonly prescribed in Taiwan. Phytoestrogens may influence the effects of estrogen in females, although their activities are weak. This study aims to identify the risk and analyze the prescription profile of commonly used phytoestrogenic herbs in Taiwan. Methods:The study analyzed women who had been prescribed phytoestrogenic herbs including coumestrol, genistein and/or daidzein between 1997 and 2007 in a fixed cohort taken from all female beneficiaries from the National Health Insurance Research Database of Taiwan. The prescription frequencies, cumulated dosages, and primary indications were listed. Results:A total of 462,861 women were included in the study, of whom ~47.0% had used phytoestrogenic herbs at least once during the study period. A total of 6,270,813 prescriptions were recorded, and more than 20% of these contained phytoestrogens. The most commonly prescribed herb and formula were Puerariae Radix and Ge gen tang (Pueraria Decoction), respectively. Most of the prescriptions were issued for diseases of the respiratory system, followed by symptoms, signs, and ill-defined conditions and diseases of the musculoskeletal system and connective tissue. Conclusion:This study shows that women who sought medical treatment from Chinese medicine doctors for relief of respiratory discomfort had a high possibility of exposure to phytoestrogenic herbs. Safety issues related to the female endocrine system should be a priority for future research. en_US dc.format.extent 103 bytes - dc.format.mimetype text/html - dc.language.iso en_US - dc.relation (關聯) Chinese Medicine,7:22 en_US dc.title (題名) Prescription profile of Chinese herbal products containing coumestrol, genestein, and/or daidzein among female users: an analysis of national health insurance data in Taiwan between 1997 and 2007 en_US dc.type (資料類型) article en dc.identifier.doi (DOI) 10.1186/1749-8546-7-22 - dc.doi.uri (DOI) http://dx.doi.org/10.1186/1749-8546-7-22 -
