Publications-Periodical Articles

Article View/Open

Publication Export

Google ScholarTM

NCCU Library

Citation Infomation

Related Publications in TAIR

題名 Quantitative Comparison of Post-Processing Methods for Reduction of Frequency Modulation Sidebands in Non-water Suppression 1H MRS
作者 蔡尚岳
Lin, Jyh-Miin ; Chuang, Tzu-Chao ; Chung, Hsiao-Wen ; Tsai, Shang-Yueh
貢獻者 應物所
關鍵詞 MRS and MRSI methods;other spectroscopic methods;artifacts and corrections;post-acquisition processing;non-water suppression;sidebands;frequency modulation;simultaneous diagonalization
日期 2013.04
上傳時間 1-Oct-2014 16:53:14 (UTC+8)
摘要 Non-water suppression MRS (NWS MRS) has several advantages. First, the unsuppressed water signal can be used as internal calibration for metabolite quantification and as a reliable frequency/phase reference for retrospective motion correction. Second, it avoids the potential artifacts caused by incomplete water suppression (WS) and extra radiofrequency deposition from WS pulses. However, the frequency modulation (FM) sidebands originating from a large water signal will distort the spectrum. Among the methods proposed to solve the problems caused by FM sidebands, post-acquisition processing methods are superior in flexibility for general use compared with experimental methods. In this study, we propose two algorithms based on advanced matrix decomposition to remove the FM sidebands. These methods, the simultaneous diagonalization (QZ) algorithm and its subsequent variant, the simultaneously generalized Schur decomposition (SGSD) algorithm, were numerically evaluated using computer simulations. In addition, we quantitatively compared the performance of these methods and the modulus method in an in vitro experiment and in vivo NWS MRS against conventional WS data. Our results show that the proposed SGSD algorithm can reduce the FM sidebands to achieve superior estimation of concentration on three major metabolites. This method can be applied directly to spectra pre-acquired under various experimental conditions without modifying the acquisition sequences.
關聯 NMR in Biomedicine, 26, 4, 400-409
資料類型 article
DOI http://dx.doi.org/10.1002/nbm.2877
dc.contributor 應物所en_US
dc.creator (作者) 蔡尚岳zh_TW
dc.creator (作者) Lin, Jyh-Miin ; Chuang, Tzu-Chao ; Chung, Hsiao-Wen ; Tsai, Shang-Yuehen_US
dc.date (日期) 2013.04en_US
dc.date.accessioned 1-Oct-2014 16:53:14 (UTC+8)-
dc.date.available 1-Oct-2014 16:53:14 (UTC+8)-
dc.date.issued (上傳時間) 1-Oct-2014 16:53:14 (UTC+8)-
dc.identifier.uri (URI) http://nccur.lib.nccu.edu.tw/handle/140.119/70402-
dc.description.abstract (摘要) Non-water suppression MRS (NWS MRS) has several advantages. First, the unsuppressed water signal can be used as internal calibration for metabolite quantification and as a reliable frequency/phase reference for retrospective motion correction. Second, it avoids the potential artifacts caused by incomplete water suppression (WS) and extra radiofrequency deposition from WS pulses. However, the frequency modulation (FM) sidebands originating from a large water signal will distort the spectrum. Among the methods proposed to solve the problems caused by FM sidebands, post-acquisition processing methods are superior in flexibility for general use compared with experimental methods. In this study, we propose two algorithms based on advanced matrix decomposition to remove the FM sidebands. These methods, the simultaneous diagonalization (QZ) algorithm and its subsequent variant, the simultaneously generalized Schur decomposition (SGSD) algorithm, were numerically evaluated using computer simulations. In addition, we quantitatively compared the performance of these methods and the modulus method in an in vitro experiment and in vivo NWS MRS against conventional WS data. Our results show that the proposed SGSD algorithm can reduce the FM sidebands to achieve superior estimation of concentration on three major metabolites. This method can be applied directly to spectra pre-acquired under various experimental conditions without modifying the acquisition sequences.en_US
dc.format.extent 298021 bytes-
dc.format.mimetype application/pdf-
dc.language.iso en_US-
dc.relation (關聯) NMR in Biomedicine, 26, 4, 400-409en_US
dc.subject (關鍵詞) MRS and MRSI methods;other spectroscopic methods;artifacts and corrections;post-acquisition processing;non-water suppression;sidebands;frequency modulation;simultaneous diagonalizationen_US
dc.title (題名) Quantitative Comparison of Post-Processing Methods for Reduction of Frequency Modulation Sidebands in Non-water Suppression 1H MRSen_US
dc.type (資料類型) articleen
dc.identifier.doi (DOI) 10.1002/nbm.2877en_US
dc.doi.uri (DOI) http://dx.doi.org/10.1002/nbm.2877en_US