| dc.contributor | 統計系 | en_US |
| dc.creator (作者) | Chen,James J. ;Hsueh, Huey-Miin ; Delongchamp, Robert R ; Lin, Chien-Ju ;Tsai, Chen-An | en_US |
| dc.creator (作者) | 薛慧敏;蔡政安 | zh_TW |
| dc.date (日期) | 2007-10 | en_US |
| dc.date.accessioned | 16-Dec-2014 10:38:52 (UTC+8) | - |
| dc.date.available | 16-Dec-2014 10:38:52 (UTC+8) | - |
| dc.date.issued (上傳時間) | 16-Dec-2014 10:38:52 (UTC+8) | - |
| dc.identifier.uri (URI) | http://nccur.lib.nccu.edu.tw/handle/140.119/72088 | - |
| dc.description.abstract (摘要) | Many researchers are concerned with the comparability and reliability of microarray gene expression data. Recent completion of the MicroArray Quality Control (MAQC) project provides a unique opportunity to assess reproducibility across multiple sites and the comparability across multiple platforms. The MAQC analysis presented for the conclusion of inter- and intra-platform comparability/reproducibility of microarray gene expression measurements is inadequate. We evaluate the reproducibility/comparability of the MAQC data for 12901 common genes in four titration samples generated from five high-density one-color microarray platforms and the TaqMan technology. We discuss some of the problems with the use of correlation coefficient as metric to evaluate the inter- and intra-platform reproducibility and the percent of overlapping genes (POG) as a measure for evaluation of a gene selection procedure by MAQC. | en_US |
| dc.format.extent | 924343 bytes | - |
| dc.format.mimetype | application/pdf | - |
| dc.language.iso | en_US | - |
| dc.relation (關聯) | BMC Bioinformatics. 2007; 8: 412. | en_US |
| dc.title (題名) | Reproducibility of microarray data: a further analysis of microarray quality control (MAQC) data | en_US |
| dc.type (資料類型) | article | en |
| dc.identifier.doi (DOI) | 10.1186/1471-2105-8-412 | en_US |
| dc.doi.uri (DOI) | http://dx.doi.org/10.1186/1471-2105-8-412 | en_US |
