| dc.contributor | 心理系 | |
| dc.creator (作者) | Chen, N.-H.;Chen, M.-C.;Li, H.-Y.;Chen, Chang-Wei;Wang, P.-C. | |
| dc.creator (作者) | 陳昌偉 | zh_TW |
| dc.date (日期) | 2011-09 | |
| dc.date.accessioned | 22-Jun-2015 15:45:48 (UTC+8) | - |
| dc.date.available | 22-Jun-2015 15:45:48 (UTC+8) | - |
| dc.date.issued (上傳時間) | 22-Jun-2015 15:45:48 (UTC+8) | - |
| dc.identifier.uri (URI) | http://nccur.lib.nccu.edu.tw/handle/140.119/76023 | - |
| dc.description.abstract (摘要) | Purpose: Using quality-of-life measures and pulse oximetry, this study developed a two-tiered prediction algorithm with an aim to prioritize sleep-disordered breathing patients for polysomnography. Methods: Data from 355 patients were evaluated to obtain their clinical information, Chinese version of Epworth sleepiness scale, and snore outcomes survey scores against respiratory disturbance index (RDI). In the first-tier screening, receiver-operating characteristics were calculated with an initial strategy of choosing optimal prediction sensitivity. The second-tier strategy investigated the association between pulse oximetry data (desaturation index of 3%) against RDI to optimize prediction specificity. Results: The "SOS score of 55 and ESS score of 9" was the optimal combination that yielded the highest sensitivity (0.603) in the first-tier screening. The strategy can includ 94.93% possible patients (probability = 0.6) with positive predictive value of 0.997. The area under the curve (AUC) was 0.88 (p < 0.001). Desaturation index of 3% would optimized specificity (0.966, probability = 0.5) in the second-tier screening to exclude 54% of innocent patients, with negative predictive values of 0.93 and AUC of 0.951 (p < 0.001). The two-tier screening model jointly excluded 4.8% of innocent subjects and prioritized 40% of severe patients for polysomnography. Conclusions: The prediction model is sufficiently accurate and feasible for large-scale population screening. © 2010 Springer-Verlag. | |
| dc.format.extent | 167156 bytes | - |
| dc.format.mimetype | application/pdf | - |
| dc.relation (關聯) | Sleep and Breathing, 15(3), 447-454 | |
| dc.subject (關鍵詞) | adult; aged; article; Epworth sleepiness scale; female; human; major clinical study; male; measurement; polysomnography; priority journal; pulse oximetry; quality of life; respiratory disturbance index; scoring system; screening; sensitivity and specificity; sleep disordered breathing; snore outcomes survey score; Adolescent; Adult; Aged; Aged, 80 and over; Cross-Cultural Comparison; Decision Support Techniques; Female; Humans; Male; Mass Screening; Middle Aged; Oximetry; Polysomnography; Quality of Life; Questionnaires; Reproducibility of Results; Retrospective Studies; ROC Curve; Sleep Apnea Syndromes; Taiwan; Young Adult | |
| dc.title (題名) | A two-tier screening model using quality-of-life measures and pulse oximetry to screen adults with sleep-disordered breathing | |
| dc.type (資料類型) | article | en |
| dc.identifier.doi (DOI) | 10.1007/s11325-010-0356-1 | |
| dc.doi.uri (DOI) | http://dx.doi.org/10.1007/s11325-010-0356-1 | |
