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題名 社會焦慮傾向者與憂鬱傾向者的病理階層模式在靜息態功能聯結網絡之初探
A preliminary study of RS-fMRI in hierarchical model of social anxiety trait and depression trait
作者 羅智宇
貢獻者 許文耀
羅智宇
關鍵詞 靜息態功能聯結網絡
階層模式
社會焦慮傾向
憂鬱傾向
rs-fMRI
hierarchical model
social anxiety trait
depression trait
日期 2015
上傳時間 27-Jul-2015 11:28:59 (UTC+8)
摘要 本研究的目的是初步探索Wang等人(2012)的模式中各因子的生理基礎，在該模式當中，社會焦慮疾患與憂鬱疾患間的結構關係，可透過高負向情感因子、低正向情感因子、害怕負向評價因子與害怕正向評價因子良好說明，然目前主要研究發現多來自問卷法研究，本研究以靜息態磁振造影做為生理方面的初探工具，以功能聯結網絡找出與因子對應的生理佐證。本研究邀請共邀請50位大學生，其中有25位是高社會焦慮傾向者，另外25位則是低社會焦慮傾向者，每位參與者都須填寫問卷與接受約15分鐘的磁振造影掃描。本研究分別以杏仁核、腦島、依核與眶額葉皮質為種子區域形成的功能聯結網絡，結果發現高社會焦慮傾向組與低社會焦慮傾向組在四組功能聯結網絡均有顯著差異；進一步分析具差異的功能聯結與量表的關係，可觀察到與負向情感因子有關的聯結同時和社會焦慮傾向及憂鬱傾向達顯著正相關，與正向情感因子有關的聯結則同時和社會焦慮傾向及憂鬱傾向達顯著負相關；分別排除社會焦慮傾向與憂鬱傾向的影響後，仍可發現和害怕正向評價因子與害怕負向評價因子具顯著相關的功能聯結。本研究的發現顯示Wang等人(2012)的模式中各因子的確有對應的腦部功能聯結，可見該模式具有生理實質性，且可良好論述與釐清心理疾患間關係，然本研究受限於種子與參與者的選擇，無法呈現該模式中因子間的關係，未來可進一步採用作業態等方法，以利更加確立腦部功能聯結與模式中各因子的關係。
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描述 碩士
國立政治大學
心理學研究所
100752006
資料來源 http://thesis.lib.nccu.edu.tw/record/#G0100752006
資料類型 thesis
dc.contributor.advisor 許文耀zh_TW
dc.contributor.author (Authors) 羅智宇zh_TW
dc.creator (作者) 羅智宇zh_TW
dc.date (日期) 2015en_US
dc.date.accessioned 27-Jul-2015 11:28:59 (UTC+8)-
dc.date.available 27-Jul-2015 11:28:59 (UTC+8)-
dc.date.issued (上傳時間) 27-Jul-2015 11:28:59 (UTC+8)-
dc.identifier (Other Identifiers) G0100752006en_US
dc.identifier.uri (URI) http://nccur.lib.nccu.edu.tw/handle/140.119/76905-
dc.description (描述) 碩士zh_TW
dc.description (描述) 國立政治大學zh_TW
dc.description (描述) 心理學研究所zh_TW
dc.description (描述) 100752006zh_TW
dc.description.abstract (摘要) 本研究的目的是初步探索Wang等人(2012)的模式中各因子的生理基礎，在該模式當中，社會焦慮疾患與憂鬱疾患間的結構關係，可透過高負向情感因子、低正向情感因子、害怕負向評價因子與害怕正向評價因子良好說明，然目前主要研究發現多來自問卷法研究，本研究以靜息態磁振造影做為生理方面的初探工具，以功能聯結網絡找出與因子對應的生理佐證。本研究邀請共邀請50位大學生，其中有25位是高社會焦慮傾向者，另外25位則是低社會焦慮傾向者，每位參與者都須填寫問卷與接受約15分鐘的磁振造影掃描。本研究分別以杏仁核、腦島、依核與眶額葉皮質為種子區域形成的功能聯結網絡，結果發現高社會焦慮傾向組與低社會焦慮傾向組在四組功能聯結網絡均有顯著差異；進一步分析具差異的功能聯結與量表的關係，可觀察到與負向情感因子有關的聯結同時和社會焦慮傾向及憂鬱傾向達顯著正相關，與正向情感因子有關的聯結則同時和社會焦慮傾向及憂鬱傾向達顯著負相關；分別排除社會焦慮傾向與憂鬱傾向的影響後，仍可發現和害怕正向評價因子與害怕負向評價因子具顯著相關的功能聯結。本研究的發現顯示Wang等人(2012)的模式中各因子的確有對應的腦部功能聯結，可見該模式具有生理實質性，且可良好論述與釐清心理疾患間關係，然本研究受限於種子與參與者的選擇，無法呈現該模式中因子間的關係，未來可進一步採用作業態等方法，以利更加確立腦部功能聯結與模式中各因子的關係。zh_TW
dc.description.tableofcontents 第一章 緒論 1
第一節 研究背景與動機 1
第二章 文獻回顧 4
第一節 社會焦慮疾患與憂鬱疾患的階層模式 4
第二節 階層模式之高低階因子及其神經生理機制 11
第三節 小結 14
第四節 研究問題與假設 17
第三章 研究方法 21
第一節 研究參與者 21
第二節 測量工具 22
第三節 實驗程序 24
第四節 磁振造影掃描 25
第五節 資料分析方法 26
第四章 研究結果 29
第一節 功能聯結網絡之差異 29
第二節 聯結網絡與量表之關聯性 46
第五章 討論 52
第一節 研究結果摘要 52
第二節 研究結果在臨床實務的意涵 54
第二節 研究限制與未來研究方向 54
參考文獻 56		zh_TW
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dc.source.uri (資料來源) http://thesis.lib.nccu.edu.tw/record/#G0100752006en_US
dc.subject (關鍵詞) 靜息態功能聯結網絡zh_TW
dc.subject (關鍵詞) 階層模式zh_TW
dc.subject (關鍵詞) 社會焦慮傾向zh_TW
dc.subject (關鍵詞) 憂鬱傾向zh_TW
dc.subject (關鍵詞) rs-fMRIen_US
dc.subject (關鍵詞) hierarchical modelen_US
dc.subject (關鍵詞) social anxiety traiten_US
dc.subject (關鍵詞) depression traiten_US
dc.title (題名) 社會焦慮傾向者與憂鬱傾向者的病理階層模式在靜息態功能聯結網絡之初探zh_TW
dc.title (題名) A preliminary study of RS-fMRI in hierarchical model of social anxiety trait and depression traiten_US
dc.type (資料類型) thesisen
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