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題名 Risk analysis of torsion and malignancy for adnexal masses during pregnancy 作者 Lin, Shu-Ling
林淑玲
Arici, Aydin
Soong, Yung-Kuei
Lee, Chyi-Long
Wang, Chin-Jung
Murk, William
Yen, Chih-Feng貢獻者 社會系 關鍵詞 adnexal masses; malignancy; Pregnancy; risk analysis; torsion 日期 2009-05 上傳時間 1-Feb-2016 15:57:11 (UTC+8) 摘要 Objective: To find the risk factors of torsion and malignancy for adnexal tumors during pregnancy. Design: Retrospective, historical cohort study. Setting: University hospital. Patient(s): Patients from 1990 to 2004 with adnexal tumors ≥4 cm during pregnancy. Intervention(s): Surgery undertaken antepartum, concurrently with cesarean delivery, or postpartum. Main Outcome Measure(s): Tumor size, progression, pathology, incidence of malignancy, and torsion. Result(s): Almost all 213 managements analyzed had good surgical and obstetric outcomes. In 174 patients who were followed through pregnancy with known tumor existence, 14.84% ± 3.05% encountered tumor torsion. Adnexal masses with sizes between 6 and 8 cm had a significantly higher risk of torsion compared with other sizes (22.41% vs. 9.48%; odds ratio 2.8, 95% confidence interval [CI], [1.1, 6.6]). Sixty percent of the torsion happened between the 10th and 17th weeks of gestation, and only 5.9% happened after 20 weeks. The incidence of malignancy was 3.4%, while that of ovarian cancer was 2.3%. Tumor diameters ≥10 cm at initial diagnosis had a higher risk of malignancy versus smaller sizes (8.77% vs. 0.85%; odds ratio 11.2, 95% CI, [1.3, 97.9]), and tumor growth rates ≥3.5 cm/week also had a significantly higher risk of malignancy versus lower rates (8.33% vs. 0.88%; odds ratio 10.2, 95% CI, [1.0, 101.2]). Conclusion(s): Adnexal tumors bearing higher risks for torsion and malignancy should be strongly considered for an aggressive strategy of management during pregnancy. 關聯 Fertility & Sterility, 91(5), 1895-1902 資料類型 article DOI http://dx.doi.org/10.1016/j.fertnstert.2008.02.014 dc.contributor 社會系 - dc.creator (作者) Lin, Shu-Ling - dc.creator (作者) 林淑玲 zh_TW dc.creator (作者) Arici, Aydin en_US dc.creator (作者) Soong, Yung-Kuei en_US dc.creator (作者) Lee, Chyi-Long en_US dc.creator (作者) Wang, Chin-Jung en_US dc.creator (作者) Murk, William en_US dc.creator (作者) Yen, Chih-Feng en_US dc.date (日期) 2009-05 - dc.date.accessioned 1-Feb-2016 15:57:11 (UTC+8) - dc.date.available 1-Feb-2016 15:57:11 (UTC+8) - dc.date.issued (上傳時間) 1-Feb-2016 15:57:11 (UTC+8) - dc.identifier.uri (URI) http://nccur.lib.nccu.edu.tw/handle/140.119/81026 - dc.description.abstract (摘要) Objective: To find the risk factors of torsion and malignancy for adnexal tumors during pregnancy. Design: Retrospective, historical cohort study. Setting: University hospital. Patient(s): Patients from 1990 to 2004 with adnexal tumors ≥4 cm during pregnancy. Intervention(s): Surgery undertaken antepartum, concurrently with cesarean delivery, or postpartum. Main Outcome Measure(s): Tumor size, progression, pathology, incidence of malignancy, and torsion. Result(s): Almost all 213 managements analyzed had good surgical and obstetric outcomes. In 174 patients who were followed through pregnancy with known tumor existence, 14.84% ± 3.05% encountered tumor torsion. Adnexal masses with sizes between 6 and 8 cm had a significantly higher risk of torsion compared with other sizes (22.41% vs. 9.48%; odds ratio 2.8, 95% confidence interval [CI], [1.1, 6.6]). Sixty percent of the torsion happened between the 10th and 17th weeks of gestation, and only 5.9% happened after 20 weeks. The incidence of malignancy was 3.4%, while that of ovarian cancer was 2.3%. Tumor diameters ≥10 cm at initial diagnosis had a higher risk of malignancy versus smaller sizes (8.77% vs. 0.85%; odds ratio 11.2, 95% CI, [1.3, 97.9]), and tumor growth rates ≥3.5 cm/week also had a significantly higher risk of malignancy versus lower rates (8.33% vs. 0.88%; odds ratio 10.2, 95% CI, [1.0, 101.2]). Conclusion(s): Adnexal tumors bearing higher risks for torsion and malignancy should be strongly considered for an aggressive strategy of management during pregnancy. - dc.format.extent 130 bytes - dc.format.mimetype text/html - dc.relation (關聯) Fertility & Sterility, 91(5), 1895-1902 - dc.subject (關鍵詞) adnexal masses; malignancy; Pregnancy; risk analysis; torsion - dc.title (題名) Risk analysis of torsion and malignancy for adnexal masses during pregnancy - dc.type (資料類型) article - dc.identifier.doi (DOI) 10.1016/j.fertnstert.2008.02.014 - dc.doi.uri (DOI) http://dx.doi.org/10.1016/j.fertnstert.2008.02.014 -
