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題名 長期助眠藥物使用之心理機轉探討 其他題名 Psychological Process of Long Term Hypnotic Use 作者 楊建銘;李信謙 貢獻者 心理學系 關鍵詞 失眠;助眠藥物;停藥;計畫行為理論;渴求;注意力偏誤
insomnia;hypnotics;theory of planned behavior;craving;attention bias日期 2013 上傳時間 19-Apr-2016 17:25:24 (UTC+8) 摘要 Many patients with chronic insomnia use hypnotics for prolonged periods of time, and find it difficult to stop using them. There are very few studies addressed this phenomenon in comparison to studies on the dependence of other substances. The current proposal contains two studies that are designed to explore the psychological mechanisms underlying long-term use of hypnotics based on theoretical models for the addiction of other substances. Study 1 will investigate this phenomenon based on the assumption that substance use is an informed choice based on cognitive beliefs. The study will recruit 180 hypnotic users and follow their hypnotic use for 12 months. Their cognitive beliefs about hypnotic use and intention of quitting drug will be assessed based on the Theory of Planned Behavior, in order to evaluate the extent to which the cognitive factors can predict long-term drug use. Study 2 will focus on the phenomenon of craving that was theorized to lead to uncontrollable substance use. Since hypnotics are used primarily to reduce sleeplessness and the associated worries and not to lead to pleasant affect, the Affective Processing Model of Negative Reinforcement (Baker, Piper, McCarthy, Majeskie, & Fiore, 2004) that stresses the influence of negative affect on drug use will be tested in the study. Twenty-four long-term hypnotic users and 24 insomnia patients who are not regular hypnotic users will be recruited for the study. They will come to the sleep laboratory in NCCU for two nights: one experimental night during which negative affect will be induced by giving negative comments on their performance on a cognitive task, and a control night with exactly the same procedure but the negative comments will be replaced by neutral comments. For both nights, assessment of subjective craving, recording of event-related potentials (ERPs) induced by pictures related to hypnotic use and neutral pictures, and measuring of heart rate, blood-pressure, and skin conductance level in reacting to drug-related cue will be conducted. Their decision on using hypnotics during the nights in the laboratory will also be recorded. It is hypothesized that subjective craving, attention bias as measured by ERPs, psychophysiological reactivities to drug-related cue, and drug-using behaviors will all be elevated by negative affect. The proposed studies will enhance the understanding of both the stable cognitive factors and situation-induced craving that might contribute to long-term hypnotic use. The findings of the studies are expected to be applied in the development of better strategies to assist patients to stop drug use. It is expected not only to eliminate the struggle of long-term hypnotic user, but also to decrease unnecessary medical expenses. 關聯 計畫編號 NSC 101-2410-H004-082-MY3 資料類型 report dc.contributor 心理學系 dc.creator (作者) 楊建銘;李信謙 zh_TW dc.date (日期) 2013 dc.date.accessioned 19-Apr-2016 17:25:24 (UTC+8) - dc.date.available 19-Apr-2016 17:25:24 (UTC+8) - dc.date.issued (上傳時間) 19-Apr-2016 17:25:24 (UTC+8) - dc.identifier.uri (URI) http://nccur.lib.nccu.edu.tw/handle/140.119/85583 - dc.description.abstract (摘要) Many patients with chronic insomnia use hypnotics for prolonged periods of time, and find it difficult to stop using them. There are very few studies addressed this phenomenon in comparison to studies on the dependence of other substances. The current proposal contains two studies that are designed to explore the psychological mechanisms underlying long-term use of hypnotics based on theoretical models for the addiction of other substances. Study 1 will investigate this phenomenon based on the assumption that substance use is an informed choice based on cognitive beliefs. The study will recruit 180 hypnotic users and follow their hypnotic use for 12 months. Their cognitive beliefs about hypnotic use and intention of quitting drug will be assessed based on the Theory of Planned Behavior, in order to evaluate the extent to which the cognitive factors can predict long-term drug use. Study 2 will focus on the phenomenon of craving that was theorized to lead to uncontrollable substance use. Since hypnotics are used primarily to reduce sleeplessness and the associated worries and not to lead to pleasant affect, the Affective Processing Model of Negative Reinforcement (Baker, Piper, McCarthy, Majeskie, & Fiore, 2004) that stresses the influence of negative affect on drug use will be tested in the study. Twenty-four long-term hypnotic users and 24 insomnia patients who are not regular hypnotic users will be recruited for the study. They will come to the sleep laboratory in NCCU for two nights: one experimental night during which negative affect will be induced by giving negative comments on their performance on a cognitive task, and a control night with exactly the same procedure but the negative comments will be replaced by neutral comments. For both nights, assessment of subjective craving, recording of event-related potentials (ERPs) induced by pictures related to hypnotic use and neutral pictures, and measuring of heart rate, blood-pressure, and skin conductance level in reacting to drug-related cue will be conducted. Their decision on using hypnotics during the nights in the laboratory will also be recorded. It is hypothesized that subjective craving, attention bias as measured by ERPs, psychophysiological reactivities to drug-related cue, and drug-using behaviors will all be elevated by negative affect. The proposed studies will enhance the understanding of both the stable cognitive factors and situation-induced craving that might contribute to long-term hypnotic use. The findings of the studies are expected to be applied in the development of better strategies to assist patients to stop drug use. It is expected not only to eliminate the struggle of long-term hypnotic user, but also to decrease unnecessary medical expenses. dc.format.extent 2791306 bytes - dc.format.mimetype application/pdf - dc.relation (關聯) 計畫編號 NSC 101-2410-H004-082-MY3 dc.subject (關鍵詞) 失眠;助眠藥物;停藥;計畫行為理論;渴求;注意力偏誤 dc.subject (關鍵詞) insomnia;hypnotics;theory of planned behavior;craving;attention bias dc.title (題名) 長期助眠藥物使用之心理機轉探討 zh_TW dc.title.alternative (其他題名) Psychological Process of Long Term Hypnotic Use dc.type (資料類型) report