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題名 Sensory gating, inhibition control and gamma oscillations in the human somatosensory cortex
作者 蔡尚岳
Cheng, Chia-Hsiung;Chan, Pei-Ying S.;Niddam, David M.;Tsai, Shang-Yueh;Hsu, Shih-Chieh;Liu, Chia-Yih
貢獻者 應物所
日期 2016-02
上傳時間 30-May-2016 15:22:48 (UTC+8)
摘要 Inhibiting the responses to irrelevant stimuli is an essential component of human cognitive function. Pre-attentive auditory sensory gating (SG), an attenuated neural activation to the second identical stimulus, has been found to be related to the performance of higher-hierarchical brain function. However, it remains unclear whether other cortical regions, such as somatosensory cortex, also possess similar characteristics, or if such a relationship is modality-specific. This study used magnetoencephalography to record neuromagnetic responses to paired-pulse electrical stimulation to median nerve in 22 healthy participants. Somatosensory SG ratio and cortical brain oscillations were obtained and compared with the behavioral performance of inhibition control, as evaluated by somatosensory and auditory Go-Nogo tasks. The results showed that somatosensory P35m SG ratio correlated with behavioral performance of inhibition control. Such relationship was also established in relation to the auditory Go-Nogo task. Finally, a higher frequency value of evoked gamma oscillations was found to relate to a better somatosensory SG ability. In conclusion, our data provided an empirical link between automatic cortical inhibition and behavioral performance of attentive inhibition control. This study invites further research on the relationships among gamma oscillations, neurophysiological indices, and behavioral performance in clinical populations in terms of SG or cortical inhibition.
關聯 Scientific Reports, Vol.4, No.6, pp.20437
資料類型 article
DOI http://dx.doi.org/10.1038/srep20437
dc.contributor 應物所
dc.creator (作者) 蔡尚岳zh_TW
dc.creator (作者) Cheng, Chia-Hsiung;Chan, Pei-Ying S.;Niddam, David M.;Tsai, Shang-Yueh;Hsu, Shih-Chieh;Liu, Chia-Yih
dc.date (日期) 2016-02
dc.date.accessioned 30-May-2016 15:22:48 (UTC+8)-
dc.date.available 30-May-2016 15:22:48 (UTC+8)-
dc.date.issued (上傳時間) 30-May-2016 15:22:48 (UTC+8)-
dc.identifier.uri (URI) http://nccur.lib.nccu.edu.tw/handle/140.119/96995-
dc.description.abstract (摘要) Inhibiting the responses to irrelevant stimuli is an essential component of human cognitive function. Pre-attentive auditory sensory gating (SG), an attenuated neural activation to the second identical stimulus, has been found to be related to the performance of higher-hierarchical brain function. However, it remains unclear whether other cortical regions, such as somatosensory cortex, also possess similar characteristics, or if such a relationship is modality-specific. This study used magnetoencephalography to record neuromagnetic responses to paired-pulse electrical stimulation to median nerve in 22 healthy participants. Somatosensory SG ratio and cortical brain oscillations were obtained and compared with the behavioral performance of inhibition control, as evaluated by somatosensory and auditory Go-Nogo tasks. The results showed that somatosensory P35m SG ratio correlated with behavioral performance of inhibition control. Such relationship was also established in relation to the auditory Go-Nogo task. Finally, a higher frequency value of evoked gamma oscillations was found to relate to a better somatosensory SG ability. In conclusion, our data provided an empirical link between automatic cortical inhibition and behavioral performance of attentive inhibition control. This study invites further research on the relationships among gamma oscillations, neurophysiological indices, and behavioral performance in clinical populations in terms of SG or cortical inhibition.
dc.format.extent 845813 bytes-
dc.format.mimetype application/pdf-
dc.relation (關聯) Scientific Reports, Vol.4, No.6, pp.20437
dc.title (題名) Sensory gating, inhibition control and gamma oscillations in the human somatosensory cortex
dc.type (資料類型) article
dc.identifier.doi (DOI) 10.1038/srep20437
dc.doi.uri (DOI) http://dx.doi.org/10.1038/srep20437