| dc.contributor | 神科所 | |
| dc.creator (作者) | 詹銘煥 | zh_TW |
| dc.creator (作者) | Wang, Ya-Jean;Chan, Ming-Huan;Chen, Linyi;Wu, Sheng-Nan;Chen, Hwei-Hisen | |
| dc.date (日期) | 2016-05 | |
| dc.date.accessioned | 5-Jun-2017 14:44:31 (UTC+8) | - |
| dc.date.available | 5-Jun-2017 14:44:31 (UTC+8) | - |
| dc.date.issued (上傳時間) | 5-Jun-2017 14:44:31 (UTC+8) | - |
| dc.identifier.uri (URI) | http://nccur.lib.nccu.edu.tw/handle/140.119/110179 | - |
| dc.description.abstract (摘要) | Resveratrol, a phytoalexin found in grapes and red wine, exhibits diverse pharmacological activities. However, relatively little is known about whether resveratrol modulates the ion channels in cortical neurons. The large-conductance calcium-activated potassium channels (BKCa) and voltage-gated sodium channels were expressed in cortical neurons and play important roles in regulation of neuronal excitability. The present study aimed to determine the effects of resveratrol on BKCa currents and voltage-gated sodium currents in cortical neurons. | |
| dc.format.extent | 1241550 bytes | - |
| dc.format.mimetype | application/pdf | - |
| dc.relation (關聯) | Journal of Biomedical Science, Vol.23, pp.47 | |
| dc.subject (關鍵詞) | Resveratrol; BKCa channel; Sodium channel; Action potential; Firing rate | |
| dc.title (題名) | Resveratrol attenuates cortical neuron activity: roles of large conductance calcium-activated potassium channels and voltage-gated sodium channels | |
| dc.type (資料類型) | article | |
| dc.identifier.doi (DOI) | 10.1186/s12929-016-0259-y | |
| dc.doi.uri (DOI) | https://dx.doi.org/10.1186/s12929-016-0259-y | |
