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題名 利用波動聚集方法探討老化對靜息態腦網路與心率變異度之影響
作者 蕭又新
貢獻者 應用物理研究所
關鍵詞 老化;功能性連結;腦島;中樞自主腦網路;靜息態
aging; functional connectivity; insula; central autonomic network; resting state
日期 2015
上傳時間 26-Dec-2017 17:49:09 (UTC+8)
摘要 本研究藉由種子體素關聯性分析這些中樞自主腦網路的核心腦區,我們的結果顯示這些所屬於中樞自主腦網路下的交感和副交感網路是潛在地存在於靜息態大腦中,其中自發性血氧濃度相依訊號的正反相關現象將其劃分為交感和副交感相關的網路。進一步的驗證指出與年齡相關的退化發生在右前腦島與邊緣整合皮質的功能性聯結,而在中樞自主腦網路中這些老化而降低的功能性聯結,很可能與老年人在減弱的記憶功能和調節穩定的身體狀態有所相關。
Autonomic nervous system (ANS) plays a critical role of quick reactions in the adaptation to the environment change, which constantly modulates visceral reflex function for a stable bodily state of task preparedness. More recently, the resting-state functional connectivity (rsFC) without subjects performing a specific cognitive task provides an alternative tool for tracking the potential neural substrates but less is known in the spontaneous neuronal activity of central autonomic network (CAN), where the CAN components encompass a sympathetic/parasympathetic network and anti-correlations with each other. We found the evidence of aging that is related to weak coupling of CAN components between right anterior insula (aINS.R) and limbic regions, which may affect the regulation of autonomic control and more specifically with memory and emotion function. Our study also provided insights about the central processing map of autonomic functions in the resting brain.
關聯 執行起迄:2015/08/01~2016/07/31
104-2112-M-004-001
資料類型 report
dc.contributor 應用物理研究所zh_Tw
dc.creator (作者) 蕭又新zh_TW
dc.date (日期) 2015en_US
dc.date.accessioned 26-Dec-2017 17:49:09 (UTC+8)-
dc.date.available 26-Dec-2017 17:49:09 (UTC+8)-
dc.date.issued (上傳時間) 26-Dec-2017 17:49:09 (UTC+8)-
dc.identifier.uri (URI) http://nccur.lib.nccu.edu.tw/handle/140.119/115445-
dc.description.abstract (摘要) 本研究藉由種子體素關聯性分析這些中樞自主腦網路的核心腦區,我們的結果顯示這些所屬於中樞自主腦網路下的交感和副交感網路是潛在地存在於靜息態大腦中,其中自發性血氧濃度相依訊號的正反相關現象將其劃分為交感和副交感相關的網路。進一步的驗證指出與年齡相關的退化發生在右前腦島與邊緣整合皮質的功能性聯結,而在中樞自主腦網路中這些老化而降低的功能性聯結,很可能與老年人在減弱的記憶功能和調節穩定的身體狀態有所相關。zh_TW
dc.description.abstract (摘要) Autonomic nervous system (ANS) plays a critical role of quick reactions in the adaptation to the environment change, which constantly modulates visceral reflex function for a stable bodily state of task preparedness. More recently, the resting-state functional connectivity (rsFC) without subjects performing a specific cognitive task provides an alternative tool for tracking the potential neural substrates but less is known in the spontaneous neuronal activity of central autonomic network (CAN), where the CAN components encompass a sympathetic/parasympathetic network and anti-correlations with each other. We found the evidence of aging that is related to weak coupling of CAN components between right anterior insula (aINS.R) and limbic regions, which may affect the regulation of autonomic control and more specifically with memory and emotion function. Our study also provided insights about the central processing map of autonomic functions in the resting brain.en_US
dc.format.extent 5724129 bytes-
dc.format.mimetype application/pdf-
dc.relation (關聯) 執行起迄:2015/08/01~2016/07/31zh_TW
dc.relation (關聯) 104-2112-M-004-001zh_TW
dc.subject (關鍵詞) 老化;功能性連結;腦島;中樞自主腦網路;靜息態zh_TW
dc.subject (關鍵詞) aging; functional connectivity; insula; central autonomic network; resting stateen_US
dc.title (題名) 利用波動聚集方法探討老化對靜息態腦網路與心率變異度之影響_TW
dc.type (資料類型) report