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題名 Adrenal insufficiency in the elderly: a nationwide study of hospitalizations in Taiwan 作者 Chen, YC;Chen, YC;Chou, LF;Chen, TJ;Hwang, SJ 貢獻者 政大財政系 日期 2010-08 上傳時間 26-Aug-2013 16:10:23 (UTC+8) 摘要 Adrenal insufficiency (AI), a life-threatening disorder, usually starts with variable nonspecific symptoms and signs of poor appetite, fatigue, fever, and gastrointestinal discomfort, and may progress to adrenal crisis with complications of electrolyte imbalance, change of consciousness or even shock. Epidemiological data about AI in the elderly population are limited. Based on nationwide hospitalization datasets in Taiwan, we retrospectively analyzed the annual incidence of AI among the elderly population (> or = 60 years old), as well as co-morbidities. The prevalence of AI increased from 6.5/10(5) (n = 1,293) in 1996 to 20.8/10(5) (n = 4,681) in 2007. In 2006, AI was newly diagnosed in 3,494 patients (1,701 women and 1,793 men), which represented an incidence of 15.5/10(5) in the whole population. Nearly four fifths (1,349 women and 1,429 men) of the patients were 60 years old and over, corresponding to an incidence of 92.4/10(5) in the elderly population. The most common co-morbidities were pneumonia (8.6%, n = 238) and urinary tract infections (6.9%, n = 193). Within the one-year observation after discharge, pneumonia was also the most frequent diagnosis in subsequent hospitalizations; besides, 178 (6.5%) patients died in the hospital and the common causes of death were respiratory failure (n = 34), septicemia (n = 23), pneumonia (n = 16), and chronic obstructive pulmonary disease (n = 9). In conclusion, the majority of the elderly have co-morbidities when AI was initially diagnosed. Infectious and pulmonary diseases as the most common co-morbidities also play a major role in subsequent hospitalizations and in-hospital deaths. 關聯 Tohoku Journal of Experimental Medicine, 221(4), 281-285 資料類型 article DOI http://dx.doi.org/10.1620/tjem.221.281 dc.contributor 政大財政系 en_US dc.creator (作者) Chen, YC;Chen, YC;Chou, LF;Chen, TJ;Hwang, SJ en_US dc.date (日期) 2010-08 en_US dc.date.accessioned 26-Aug-2013 16:10:23 (UTC+8) - dc.date.available 26-Aug-2013 16:10:23 (UTC+8) - dc.date.issued (上傳時間) 26-Aug-2013 16:10:23 (UTC+8) - dc.identifier.uri (URI) http://nccur.lib.nccu.edu.tw/handle/140.119/59135 - dc.description.abstract (摘要) Adrenal insufficiency (AI), a life-threatening disorder, usually starts with variable nonspecific symptoms and signs of poor appetite, fatigue, fever, and gastrointestinal discomfort, and may progress to adrenal crisis with complications of electrolyte imbalance, change of consciousness or even shock. Epidemiological data about AI in the elderly population are limited. Based on nationwide hospitalization datasets in Taiwan, we retrospectively analyzed the annual incidence of AI among the elderly population (> or = 60 years old), as well as co-morbidities. The prevalence of AI increased from 6.5/10(5) (n = 1,293) in 1996 to 20.8/10(5) (n = 4,681) in 2007. In 2006, AI was newly diagnosed in 3,494 patients (1,701 women and 1,793 men), which represented an incidence of 15.5/10(5) in the whole population. Nearly four fifths (1,349 women and 1,429 men) of the patients were 60 years old and over, corresponding to an incidence of 92.4/10(5) in the elderly population. The most common co-morbidities were pneumonia (8.6%, n = 238) and urinary tract infections (6.9%, n = 193). Within the one-year observation after discharge, pneumonia was also the most frequent diagnosis in subsequent hospitalizations; besides, 178 (6.5%) patients died in the hospital and the common causes of death were respiratory failure (n = 34), septicemia (n = 23), pneumonia (n = 16), and chronic obstructive pulmonary disease (n = 9). In conclusion, the majority of the elderly have co-morbidities when AI was initially diagnosed. Infectious and pulmonary diseases as the most common co-morbidities also play a major role in subsequent hospitalizations and in-hospital deaths. en_US dc.language.iso en_US - dc.relation (關聯) Tohoku Journal of Experimental Medicine, 221(4), 281-285 en_US dc.title (題名) Adrenal insufficiency in the elderly: a nationwide study of hospitalizations in Taiwan en_US dc.type (資料類型) article en dc.identifier.doi (DOI) 10.1620/tjem.221.281 en_US dc.doi.uri (DOI) http://dx.doi.org/10.1620/tjem.221.281 en_US
