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題名 The Joint Model of the Logistic Model and Linear Random Effect Model - An Application to Predict Orthostatic Hypertension for Subacute Stroke Patients
作者 Hwang, Yi-Ting ; Tsai, Hao-Yun ; Chang, Yeu-Jhy ; Kuo, Hsun-Chih ; Wang, Chun-Chao
郭訓志
貢獻者 統計系
關鍵詞 Orthostatic hypotension ; Joint model ; Logistic regression ; Random effect model ; Two stage model ; Stroke
日期 2011.01
上傳時間 17-Apr-2014 17:44:47 (UTC+8)
摘要 Stroke is a common acute neurologic and disabling disease. Orthostatic hypertension (OH) is one of the catastrophic cardiovascular conditions. If a stroke patient has OH, he/she has higher chance to fall or syncope during the following courses of treatment. This can result in possible bone fracture and the burden of medical cost therefore increases. How to early diagnose OH is clinically important. However, there is no obvious time-saving method for clinical evaluation except to check the postural blood pressure.This paper uses clinical data to identify potential clinical factors that are associated with OH. The data include repeatedly observed blood pressure, and the patient’s basic characteristics and clinical symptoms. A traditional logistic regression is not appropriate for such data. The paper modifies the two-stage model proposed by Tsiatis et al. (1995) and the joint model proposed by Wulfsohn and Tsiatis (1997) to take into account of a sequence of repeated measures to predict OH. The large sample properties of estimators of modified models are derived. Monte Carlo simulations are performed to evaluate the accuracy of these estimators. A case study is presented.
關聯 Computational Statistics and Data Analysis, 55(1), 914-923
資料來源 http://dx.doi.org/10.1016/j.csda.2010.07.024
資料類型 article
DOI http://dx.doi.org/http://dx.doi.org/10.1016/j.csda.2010.07.024
dc.contributor 統計系en_US
dc.creator (作者) Hwang, Yi-Ting ; Tsai, Hao-Yun ; Chang, Yeu-Jhy ; Kuo, Hsun-Chih ; Wang, Chun-Chaoen_US
dc.creator (作者) 郭訓志zh_TW
dc.date (日期) 2011.01en_US
dc.date.accessioned 17-Apr-2014 17:44:47 (UTC+8)-
dc.date.available 17-Apr-2014 17:44:47 (UTC+8)-
dc.date.issued (上傳時間) 17-Apr-2014 17:44:47 (UTC+8)-
dc.identifier.uri (URI) http://nccur.lib.nccu.edu.tw/handle/140.119/65491-
dc.description.abstract (摘要) Stroke is a common acute neurologic and disabling disease. Orthostatic hypertension (OH) is one of the catastrophic cardiovascular conditions. If a stroke patient has OH, he/she has higher chance to fall or syncope during the following courses of treatment. This can result in possible bone fracture and the burden of medical cost therefore increases. How to early diagnose OH is clinically important. However, there is no obvious time-saving method for clinical evaluation except to check the postural blood pressure.This paper uses clinical data to identify potential clinical factors that are associated with OH. The data include repeatedly observed blood pressure, and the patient’s basic characteristics and clinical symptoms. A traditional logistic regression is not appropriate for such data. The paper modifies the two-stage model proposed by Tsiatis et al. (1995) and the joint model proposed by Wulfsohn and Tsiatis (1997) to take into account of a sequence of repeated measures to predict OH. The large sample properties of estimators of modified models are derived. Monte Carlo simulations are performed to evaluate the accuracy of these estimators. A case study is presented.en_US
dc.format.extent 533030 bytes-
dc.format.mimetype application/pdf-
dc.language.iso en_US-
dc.relation (關聯) Computational Statistics and Data Analysis, 55(1), 914-923en_US
dc.source.uri (資料來源) http://dx.doi.org/10.1016/j.csda.2010.07.024en_US
dc.subject (關鍵詞) Orthostatic hypotension ; Joint model ; Logistic regression ; Random effect model ; Two stage model ; Strokeen_US
dc.title (題名) The Joint Model of the Logistic Model and Linear Random Effect Model - An Application to Predict Orthostatic Hypertension for Subacute Stroke Patientsen_US
dc.type (資料類型) articleen
dc.identifier.doi (DOI) 10.1016/j.csda.2010.07.024en_US
dc.doi.uri (DOI) http://dx.doi.org/http://dx.doi.org/10.1016/j.csda.2010.07.024en_US