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題名 Total Choline Level on MRS Predicts Overall Survival for Endometrial Cancer and Correlates with Tissue Choline Metabolism
作者 蔡尚岳
Tsai, Shang-Yueh
Lin, Gigin;Lin, Yu-Chun;Lin, Chiao-Yun;Wu, Ren-Chin;Lai, Chyong-Huey
貢獻者 應物所
日期 2020-08
上傳時間 29-Jul-2022 15:47:24 (UTC+8)
摘要 Endometrial cancer is the most common gynecologic cancer in the developed countries but responses differently to the standard treatment. We aim to investigate and characterize the values of endometrial total choline levels on 1H MR spectroscopy in predicting overall survival, with tissue metabolomics and biochemistry corroboration. We found that increased total choline levels on MRS depicted high-risk cancer group for nodal metastasis, overall survival and disease-free survival for endometrial cancers, supported by increased tissue GPC levels and overexpression of EDI3.
關聯 2020 Proceedings of International Society for Magnetic Resonance in Medicine, International Society for Magnetic Resonance in Medicine, pp.0586
資料類型 conference
dc.contributor 應物所
dc.creator (作者) 蔡尚岳
dc.creator (作者) Tsai, Shang-Yueh
dc.creator (作者) Lin, Gigin;Lin, Yu-Chun;Lin, Chiao-Yun;Wu, Ren-Chin;Lai, Chyong-Huey
dc.date (日期) 2020-08
dc.date.accessioned 29-Jul-2022 15:47:24 (UTC+8)-
dc.date.available 29-Jul-2022 15:47:24 (UTC+8)-
dc.date.issued (上傳時間) 29-Jul-2022 15:47:24 (UTC+8)-
dc.identifier.uri (URI) http://nccur.lib.nccu.edu.tw/handle/140.119/140957-
dc.description.abstract (摘要) Endometrial cancer is the most common gynecologic cancer in the developed countries but responses differently to the standard treatment. We aim to investigate and characterize the values of endometrial total choline levels on 1H MR spectroscopy in predicting overall survival, with tissue metabolomics and biochemistry corroboration. We found that increased total choline levels on MRS depicted high-risk cancer group for nodal metastasis, overall survival and disease-free survival for endometrial cancers, supported by increased tissue GPC levels and overexpression of EDI3.
dc.format.extent 104 bytes-
dc.format.mimetype text/html-
dc.relation (關聯) 2020 Proceedings of International Society for Magnetic Resonance in Medicine, International Society for Magnetic Resonance in Medicine, pp.0586
dc.title (題名) Total Choline Level on MRS Predicts Overall Survival for Endometrial Cancer and Correlates with Tissue Choline Metabolism
dc.type (資料類型) conference