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題名 Zolpidem use and the risk of arrhythmia: a nationwide population-based cohort study in Taiwan
作者 陳玠文
Chen, Hong-Jhe;Ou, Hsun;Shen, Jia-Ying;Chung, Chi-Hsiang;Hung, Yuan;Chen, Chieh-Wen;Stubbs, Brendon;Chien, Wu-Chien;Chen, Tien-Yu
貢獻者 神科所
關鍵詞 Arrhythmia; Benzodiazepines; Cardiovascular disease; Zolpidem
日期 2026-04
上傳時間 7-May-2026 10:32:44 (UTC+8)
摘要 Zolpidem is a common sleep medication, but its cardiac safety was previously unclear. This study used Taiwan’s national database to analyze over 450 000 individuals and found that zolpidem use is associated with a nearly 2-fold increase in the risk of arrhythmia, particularly fast heartbeats like atrial flutter and paroxysmal tachycardia. These findings suggest that patients and doctors should carefully weigh the cardiac risks before starting treatment, and those with existing heart conditions may benefit from regular heart monitoring while using this medication to ensure overall safety.
關聯 Journal of the Chinese Medical Association, Vol.89, No.4, pp.284-292
資料類型 article
DOI https://doi.org/10.1097/jcma.0000000000001360
dc.contributor 神科所
dc.creator (作者) 陳玠文
dc.creator (作者) Chen, Hong-Jhe;Ou, Hsun;Shen, Jia-Ying;Chung, Chi-Hsiang;Hung, Yuan;Chen, Chieh-Wen;Stubbs, Brendon;Chien, Wu-Chien;Chen, Tien-Yu
dc.date (日期) 2026-04
dc.date.accessioned 7-May-2026 10:32:44 (UTC+8)-
dc.date.available 7-May-2026 10:32:44 (UTC+8)-
dc.date.issued (上傳時間) 7-May-2026 10:32:44 (UTC+8)-
dc.identifier.uri (URI) https://ah.lib.nccu.edu.tw/item?item_id=182358-
dc.description.abstract (摘要) Zolpidem is a common sleep medication, but its cardiac safety was previously unclear. This study used Taiwan’s national database to analyze over 450 000 individuals and found that zolpidem use is associated with a nearly 2-fold increase in the risk of arrhythmia, particularly fast heartbeats like atrial flutter and paroxysmal tachycardia. These findings suggest that patients and doctors should carefully weigh the cardiac risks before starting treatment, and those with existing heart conditions may benefit from regular heart monitoring while using this medication to ensure overall safety.
dc.format.extent 109 bytes-
dc.format.mimetype text/html-
dc.relation (關聯) Journal of the Chinese Medical Association, Vol.89, No.4, pp.284-292
dc.subject (關鍵詞) Arrhythmia; Benzodiazepines; Cardiovascular disease; Zolpidem
dc.title (題名) Zolpidem use and the risk of arrhythmia: a nationwide population-based cohort study in Taiwan
dc.type (資料類型) article
dc.identifier.doi (DOI) 10.1097/JCMA.0000000000001360
dc.doi.uri (DOI) https://doi.org/10.1097/jcma.0000000000001360