1. NCCU Academic Hub
  2. Publications
  3. College of Science
  4. Proceedings
  5. Item

Publications-Proceedings

Article View/Open

Publication Export

Google ScholarTM

NCCU Library

Citation Infomation

Related Publications in TAIR

題名 Licking performance on a choice procedure under dopamine receptor blockade in the rat
作者 廖瑞銘
Wang, S. H.
貢獻者 國立政治大學心理學系
日期 2000
上傳時間 11-Jul-2013 13:54:12 (UTC+8)
Publisher Society for neuroscience, Society for neuroscience
摘要 Although interference with the dopamine (DA) systems has been shown to impair instrumental behavior, it may have a little or no effect on the basic processes of motivation (Salamone, 1992). The present study was designed to directly examine the effects of DA receptor antagonists on licking in a choice situation. The food-deprived rats were trained to lick for the solution from either a high-positioned 20% sucrose or the low-positioned 15% sucrose. After 10 to 14 sessions of training, the subject significantly preferred to consume the high-positioned 20% sucrose solution. Drug treatment was conducted by IP injection of SCH23390 (0.05, 0.1, 0.2 mg/kg), raclopride (0.1, 0.2 mg/kg), or haloperidol (0.05, 0.1 mg/kg). While the licking of high-positioned 20% sucrose was dose-related suppressed by all three drugs, the concurrent consumption of the low-positioned 15% sucrose was significantly enhanced. However, a more experience of licking on the low-positioned liquid was required for the subject to produce such a behavioral reallocation under raclopride and haloperidol treatments, but not under SCH23390. These results indicate that the motivational processing can be adjusted to counteract behavioral changes under DA receptor blockade.
資料類型 conference
dc.contributor 國立政治大學心理學系en
dc.creator (作者) 廖瑞銘zh_TW
dc.creator (作者) Wang, S. H.en
dc.date (日期) 2000-
dc.date.accessioned 11-Jul-2013 13:54:12 (UTC+8)-
dc.date.available 11-Jul-2013 13:54:12 (UTC+8)-
dc.date.issued (上傳時間) 11-Jul-2013 13:54:12 (UTC+8)-
dc.identifier.uri (URI) http://nccur.lib.nccu.edu.tw/handle/140.119/58744-
dc.description.abstract (摘要) Although interference with the dopamine (DA) systems has been shown to impair instrumental behavior, it may have a little or no effect on the basic processes of motivation (Salamone, 1992). The present study was designed to directly examine the effects of DA receptor antagonists on licking in a choice situation. The food-deprived rats were trained to lick for the solution from either a high-positioned 20% sucrose or the low-positioned 15% sucrose. After 10 to 14 sessions of training, the subject significantly preferred to consume the high-positioned 20% sucrose solution. Drug treatment was conducted by IP injection of SCH23390 (0.05, 0.1, 0.2 mg/kg), raclopride (0.1, 0.2 mg/kg), or haloperidol (0.05, 0.1 mg/kg). While the licking of high-positioned 20% sucrose was dose-related suppressed by all three drugs, the concurrent consumption of the low-positioned 15% sucrose was significantly enhanced. However, a more experience of licking on the low-positioned liquid was required for the subject to produce such a behavioral reallocation under raclopride and haloperidol treatments, but not under SCH23390. These results indicate that the motivational processing can be adjusted to counteract behavioral changes under DA receptor blockade.en
dc.language zh_TWen
dc.language.iso en_US-
dc.publisher (Publisher) Society for neuroscience, Society for neuroscienceen
dc.title (題名) Licking performance on a choice procedure under dopamine receptor blockade in the raten
dc.type (資料類型) conferenceen